NFAT2 Monoclonal Antibody
- SKU:
- CAB23485
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | NFAT2 Monoclonal Antibody |
| Product Code: | CAB23485 |
| Reactivity: | Human, Mouse |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC57041 |
| Reactivity: | Human, Mouse |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:2000-1:8000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | Daudi, Jurkat, RAW 264.7 |
| Cellular Location: | Cytoplasm, Nucleus |
The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 10-305 of human NFAT2 (NP_001265598.1). |
| Sequence: | SKFPL GPAAA VFGRG ETLGP APRAG GTMKS AEEEH YGYAS SNVSP ALPLP TAHST LPAPC HNLQT STPGI IPPAD HPSGY GAALD GGPAG YFLSS GHTRP DGAPA LESPR IEITS CLGLY HNNNQ FFHDV EVEDV LPSSK RSPST ATLSL PSLEA YRDPS CLSPA SSLSS RSCNS EASSY ESNYS YPYAS PQTSP WQSPC VSPKT TDPEE GFPRG LGACT LLGSP RHSPS TSPRA SVTEE SWLGA RSSRP ASPCN KRKYS LNGRQ PPYSP HHSPT PSPHG SPRVS VTDDS WLGNT T |
| Synonyms: | NFAT2, NFATc, NF-ATC, NF-ATc1.2 |
| Calculated MW: | 101kDa |
| Observed MW: | 75-140kDa |
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