NF-kB p65/RelA Monoclonal Antibody (CAB22331)
- SKU:
- CAB22331
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Reactivity:
- NHP - Monkey
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
- Applications:
- IP
Description
| Product Name: | NF-kB p65/RelA Monoclonal Antibody |
| Product Code: | CAB22331 |
| Reactivity: | Human, Mouse, Rat, Monkey |
| Applications: | Western blotting, Immunohistochemistry, Immunofluorescence, Immunoprecipitation |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC51088 |
| Reactivity: | Human, Mouse, Rat, Monkey |
| Tested Applications: | WB, IHC-P, IF/ICC, IP, ChIP, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence, Immunoprecipitation |
| Recommended Dilution: | WB 1:2000-1:10000, IHC-P 1:50-1:200, IF/ICC 1:50-1:200, ChIP 1:50-1:200, IP 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | HeLa, PC-12, NIH/3T3, Mouse lung |
| Cellular Location: | Cytoplasm, Nucleus |
| Customer Validation: | WB(Homo sapiens) |
NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 450-551 of human NF-kB p65/RelA (NP_068810.3). |
| Sequence: | LGALL GNSTD PAVFT DLASV DNSEF QQLLN QGIPV APHTT EPMLM EYPEA ITRLV TGAQR PPDPA PAPLG APGLP NGLLS GDEDF SSIAD MDFSA LLSQI SS |
| Synonyms: | p65, CMCU, NFKB3, AIF3BL3 |
| Calculated MW: | 58kDa/59kDa/60kDa |
| Observed MW: | 65kDa |
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