NEUROD1 Polyclonal Antibody
- SKU:
- CAB24669
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- IF
Description
| Product Name: | NEUROD1 Polyclonal Antibody |
| Product Code: | CAB24669 |
| Reactivity: | Mouse, Rat |
| Applications: | Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Mouse, Rat |
| Tested Applications: | IF/ICC, ELISA |
| Key Applications: | Immunofluorescence |
| Recommended Dilution: | IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Cellular Location: | Cytoplasm, Nucleus |
This gene encodes a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. The protein forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box. It regulates expression of the insulin gene, and mutations in this gene result in type II diabetes mellitus.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-136 of human NEUROD1 (NP_002491.2). |
| Sequence: | MTKSY SESGL MGEPQ PQGPP SWTDE CLSSQ DEEHE ADKKE DDLET MNAEE DSLRN GGEEE DEDED LEEEE EEEEE DDDQK PKRRG PKKKK MTKAR LERFK LRRMK ANARE RNRMH GLNAA LDNLR KVVPC YSKTQ K |
| Synonyms: | T2D, BETA2, BHF-1, MODY6, NEUROD, bHLHa3 |
| Calculated MW: | 40kDa |
| Observed MW: | Refer to figures |
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