NEURL1 Antibody (PACO05699)
- SKU:
- PACO05699
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | NEURL1 Antibody (PACO05699) |
| Antibody SKU: | PACO05699 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:40000, WB:1:500-1:2000, IHC:1:100-1:300 |
| Species Reactivity: | Human |
| Immunogen: | Synthesized peptide derived from the Internal region of human Neuralized-1. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | NEURL; NEURL1; NEURL1A; RNF67; Neuralized-like protein 1A; h-neu; h-neuralized 1; RING finger protein 67 |
| UniProt Protein Function: | NEURL1: May function as an E3 ubiquitin-protein ligase to activate monoubiquitination of JAG1, thereby regulating the Notch pathway. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Tumor suppressor; Ubiquitin ligase; Ligase; Motility/polarity/chemotaxis; EC 6.3.2.-; Cell development/differentiation; Ubiquitin conjugating systemChromosomal Location of Human Ortholog: 10q25.1Cellular Component: dendritic spine; perikaryon; plasma membrane; postsynaptic densityMolecular Function: translation factor activity, non-nucleic acid binding; ubiquitin-protein ligase activityBiological Process: negative regulation of cell proliferation; negative regulation of Notch signaling pathway; nervous system development; positive regulation of apoptosis; positive regulation of filopodium formation; positive regulation of long-term neuronal synaptic plasticity; protein monoubiquitination |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | O76050 |
| NCBI GenInfo Identifier: | 61214427 |
| NCBI Gene ID: | 9148 |
| NCBI Accession: | O76050.1 |
| UniProt Secondary Accession: | O76050,Q5TDR2, Q5TDR3, Q8TAN0, Q9H463 |
| UniProt Related Accession: | O76050 |
| Molecular Weight: | 60,030 Da |
| NCBI Full Name: | E3 ubiquitin-protein ligase NEURL1 |
| NCBI Synonym Full Names: | neuralized E3 ubiquitin protein ligase 1 |
| NCBI Official Symbol: | NEURL1 |
| NCBI Official Synonym Symbols: | neu; NEUR1; NEURL; RNF67; neu-1; bA416N2.1 |
| NCBI Protein Information: | E3 ubiquitin-protein ligase NEURL1 |
| UniProt Protein Name: | E3 ubiquitin-protein ligase NEURL1 |
| UniProt Synonym Protein Names: | Neuralized-like protein 1A; h-neu; h-neuralized 1; RING finger protein 67 |
| Protein Family: | E3 ubiquitin-protein ligase |
| UniProt Gene Name: | NEURL1 |
| UniProt Entry Name: | NEUL1_HUMAN |
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