Description
| Product Name: | NEDD8 Monoclonal Antibody |
| Product Code: | CAB22568 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC58460 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:2000-1:20000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | HeLa, 293T, RAW264.7, NIH/3T3, C6, Mouse brain |
| Cellular Location: | Nucleus |
Enables ubiquitin protein ligase binding activity. Acts upstream of or within protein neddylation. Located in cytosol and nucleoplasm. Biomarker of Parkinson's disease and malignant astrocytoma.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-81 of human NEDD8 (NP_006147.1). |
| Sequence: | MLIKV KTLTG KEIEI DIEPT DKVER IKERV EEKEG IPPQQ QRLIY SGKQM NDEKT AADYK ILGGS VLHLV LALRG GGGLR Q |
| Synonyms: | NEDD-8 |
| Calculated MW: | 9kDa |
| Observed MW: | 9kDa |