Description
| Antibody Name: | NECAP1 Antibody (PACO10804) |
| Antibody SKU: | PACO10804 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human NECAP1 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | NECAP endocytosis associated 1;NECAP1;DKFZP566B183;MGC131900 ; |
| UniProt Protein Function: | NECAP1: Involved in endocytosis. Belongs to the NECAP family. 2 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 12p13.31Cellular Component: clathrin vesicle coat; plasma membrane; coated pitBiological Process: protein transport; endocytosisDisease: Epileptic Encephalopathy, Early Infantile, 21 |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a protein containing two characteristic WXXF motifs. The encoded protein localizes to clathrin-coated vesicles, where it binds components of the adapter protein complexes and aids in endocytosis. Loss of function of this gene results in early infantile epileptic encephalopathy-21. There is a pseudogene for this gene on chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014] |
| UniProt Code: | Q8NC96 |
| NCBI GenInfo Identifier: | 31542528 |
| NCBI Gene ID: | 25977 |
| NCBI Accession: | NP_056324.2 |
| UniProt Secondary Accession: | Q8NC96,Q2NL73, Q5XG95, Q6NWY6, Q8N153, Q8NCB0, Q9BU52 Q9Y407 |
| UniProt Related Accession: | Q8NC96 |
| Molecular Weight: | 11,444 Da |
| NCBI Full Name: | adaptin ear-binding coat-associated protein 1 |
| NCBI Synonym Full Names: | NECAP endocytosis associated 1 |
| NCBI Official Symbol: | NECAP1 |
| NCBI Official Synonym Symbols: | EIEE21 |
| NCBI Protein Information: | adaptin ear-binding coat-associated protein 1 |
| UniProt Protein Name: | Adaptin ear-binding coat-associated protein 1 |
| UniProt Synonym Protein Names: | NECAP endocytosis-associated protein 1; NECAP-1 |
| Protein Family: | Adaptin ear-binding coat-associated protein |
| UniProt Gene Name: | NECAP1 |
| UniProt Entry Name: | NECP1_HUMAN |