NDUFS7 Polyclonal Antibody
- SKU:
- CAB24466
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | NDUFS7 Polyclonal Antibody |
| Product Code: | CAB24466 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:1000-1:5000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | A549, HeLa, 293T |
| Cellular Location: | Mitochondrion |
This gene encodes a protein that is a subunit of one of the complexes that forms the mitochondrial respiratory chain. This protein is one of over 40 subunits found in complex I, the nicotinamide adenine dinucleotide (NADH):ubiquinone oxidoreductase. This complex functions in the transfer of electrons from NADH to the respiratory chain, and ubiquinone is believed to be the immediate electron acceptor for the enzyme. Mutations in this gene cause Leigh syndrome due to mitochondrial complex I deficiency, a severe neurological disorder that results in bilaterally symmetrical necrotic lesions in subcortical brain regions.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 80-160 of human NDUFS7 (NP_077718.3). |
| Sequence: | WPMTF GLACC AVEMM HMAAP RYDMD RFGVV FRASP RQSDV MIVAG TLTNK MAPAL RKVYD QMPEP RYVVS MGSCA NGGGY Y |
| Synonyms: | NDUFS7, CI-20, CI-20KD, MY017, PSST, NADH:ubiquinone oxidoreductase core subunit S7 |
| Calculated MW: | 22kDa/23kDa |
| Observed MW: | 20kDa |
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