NDNL2 Antibody (PACO19227)
- SKU:
- PACO19227
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | NDNL2 Antibody (PACO19227) |
| Antibody SKU: | PACO19227 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:50-1:200 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthetic peptide of human NDNL2 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO19227(NDNL2 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-4: Hela cells, human prostate tissue, A172 cells, mouse liver tissue tissue, Primary antibody: PACO19227(NDNL2 Antibody) at dilution 1/1500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds. |
 | The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO19227(NDNL2 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | The protein encoded by this gene is part of the SMC5-6 chromatin reorganizing complex and is a member of the MAGE superfamily. This is an intronless gene. Component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs). |
| Synonyms: | necdin-like 2 |
| UniProt Protein Function: | |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene is part of the SMC5-6 chromatin reorganizing complex and is a member of the MAGE superfamily. This is an intronless gene. [provided by RefSeq, May 2011] |
| UniProt Code: | Q96MG7 |
| NCBI GenInfo Identifier: | 1559725024 |
| NCBI Gene ID: | 56160 |
| NCBI Accession: | NP_001035983 |
| UniProt Secondary Accession: | Q96MG7 |
| UniProt Related Accession: | Q96MG7 |
| Molecular Weight: | 34 |
| NCBI Full Name: | serpin A9 isoform B |
| NCBI Synonym Full Names: | NSE3 homolog, SMC5-SMC6 complex component |
| NCBI Official Symbol: | NSMCE3 |
| NCBI Official Synonym Symbols: | HCA4; LICS; NSE3; NDNL2; MAGEG1; MAGEL3 |
| NCBI Protein Information: | non-structural maintenance of chromosomes element 3 homolog |
| UniProt Protein Name: | |
| UniProt Synonym Protein Names: | |
| Protein Family: | |
| UniProt Gene Name: | |
| UniProt Entry Name: |
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