Description
Antibody Name: | NCR3LG1 Antibody (PACO46638) |
Antibody SKU: | PACO46638 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Recombinant Human Natural cytotoxicity triggering receptor 3 ligand 1 protein (25-262AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: B7H6 antibody at 2 µg/ml. Lane 1: Mouse heart tissue. Lane 2: Mouse liver tissue. Lane 3: Mouse brain tissue. Lane 4: Hela whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 51 kDa. Observed band size: 51, 38, 32 kDa.. | |
Immunofluorescent analysis of HepG2 cells using PACO46638 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). | |
Immunohistochemistry of paraffin-embedded human melanoma using PACO46638 at dilution of 1:100. |
Background: | Triggers NCR3-dependent natural killer cell activation. |
Synonyms: | Natural cytotoxicity triggering receptor 3 ligand 1 (B7 homolog 6) (B7-H6), NCR3LG1, B7H6 |
UniProt Protein Function: | B7-H6: Triggers NCR3-dependent natural killer cell activation. |
UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 11p15.1 Cellular Component: plasma membrane Biological Process: regulation of immune response |
NCBI Summary: | B7H6 belongs to the B7 family (see MIM 605402) and is selectively expressed on tumor cells. Interaction of B7H6 with NKp30 (NCR3; MIM 611550) results in natural killer (NK) cell activation and cytotoxicity (Brandt et al., 2009 [PubMed 19528259]).[supplied by OMIM, Jan 2011] |
UniProt Code: | Q68D85 |
NCBI GenInfo Identifier: | 74708829 |
NCBI Gene ID: | 374383 |
NCBI Accession: | Q68D85.1 |
UniProt Secondary Accession: | Q68D85,Q7Z3M6, |
UniProt Related Accession: | Q68D85 |
Molecular Weight: | 50,827 Da |
NCBI Full Name: | Natural cytotoxicity triggering receptor 3 ligand 1 |
NCBI Synonym Full Names: | natural killer cell cytotoxicity receptor 3 ligand 1 |
NCBI Official Symbol: | NCR3LG1 |
NCBI Official Synonym Symbols: | B7H6; B7-H6; DKFZp686O24166 |
NCBI Protein Information: | natural cytotoxicity triggering receptor 3 ligand 1 |
UniProt Protein Name: | Natural cytotoxicity triggering receptor 3 ligand 1 |
UniProt Synonym Protein Names: | B7 homolog 6; B7-H6 |
Protein Family: | Natural cytotoxicity triggering receptor |
UniProt Gene Name: | NCR3LG1 |
UniProt Entry Name: | NR3L1_HUMAN |