NCR3 Monoclonal Antibody
- SKU:
- CAB24295
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IF
Description
| Product Name: | NCR3 Monoclonal Antibody |
| Product Code: | CAB24295 |
| Reactivity: | Human |
| Applications: | Western blotting, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC60018 |
| Reactivity: | Human |
| Tested Applications: | WB, IF/ICC, FC, FC(Intra), ELISA |
| Key Applications: | Western blotting, Immunofluorescence |
| Recommended Dilution: | WB 1:500-1:1000, IF/ICC 1:50-1:200, FC(Intra) 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | 293T transfected with NCR3 (Human) |
| Cellular Location: | Plasma membrane |
The protein encoded by this gene is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 19-135 of human CD337/NKp30 (NP_667341.1). |
| Sequence: | LWVSQ PPEIR TLEGS SAFLP CSFNA SQGRL AIGSV TWFRD EVVPG KEVRN GTPEF RGRLA PLASS RFLHD HQAEL HIRDV RGHDA SIYVC RVEVL GLGVG TGNGT RLVVE KEHPQ LG |
| Synonyms: | NCR3, 1C7, CD337, LY117, MALS, NKp30, natural cytotoxicity triggering receptor 3 |
| Calculated MW: | 16kDa/17kDa/18kDa/19kDa/20kDa/21kDa |
| Observed MW: | 30kDa |
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