Description
Product Name: | NCR3 Monoclonal Antibody |
Product Code: | CAB24295 |
Reactivity: | Human |
Applications: | Western blotting, Immunofluorescence |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC60018 |
Reactivity: | Human |
Tested Applications: | WB, IF/ICC, FC, FC(Intra), ELISA |
Key Applications: | Western blotting, Immunofluorescence |
Recommended Dilution: | WB 1:500-1:1000, IF/ICC 1:50-1:200, FC(Intra) 1:500-1:1000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | 293T transfected with NCR3 (Human) |
Cellular Location: | Plasma membrane |
The protein encoded by this gene is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 19-135 of human CD337/NKp30 (NP_667341.1). |
Sequence: | LWVSQ PPEIR TLEGS SAFLP CSFNA SQGRL AIGSV TWFRD EVVPG KEVRN GTPEF RGRLA PLASS RFLHD HQAEL HIRDV RGHDA SIYVC RVEVL GLGVG TGNGT RLVVE KEHPQ LG |
Synonyms: | NCR3, 1C7, CD337, LY117, MALS, NKp30, natural cytotoxicity triggering receptor 3 |
Calculated MW: | 16kDa/17kDa/18kDa/19kDa/20kDa/21kDa |
Observed MW: | 30kDa |