Description
| Antibody Name: | NCLN Antibody (PACO10761) |
| Antibody SKU: | PACO10761 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human NCLN |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | nicalin homolog (zebrafish); |
| UniProt Protein Function: | NCLN: May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning. Belongs to the nicastrin family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 19p13.3Cellular Component: endoplasmic reticulum membrane; membrane; integral to membraneMolecular Function: protein bindingBiological Process: regulation of signal transduction |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q969V3 |
| NCBI GenInfo Identifier: | 51873031 |
| NCBI Gene ID: | 56926 |
| NCBI Accession: | NP_064555.2 |
| UniProt Secondary Accession: | Q969V3,O75252, Q6FI60, Q6ZMB7, Q8TAT7, Q96H48, Q96IS7 Q9BQH9, Q9BTX4, Q9NPP2 |
| UniProt Related Accession: | Q969V3 |
| Molecular Weight: | 62,974 Da |
| NCBI Full Name: | nicalin |
| NCBI Synonym Full Names: | nicalin |
| NCBI Official Symbol: | NCLN |
| NCBI Official Synonym Symbols: | NET59 |
| NCBI Protein Information: | nicalin; nicastrin-like protein; nicalin homolog (zebrefish) |
| UniProt Protein Name: | Nicalin |
| UniProt Synonym Protein Names: | Nicastrin-like protein |
| Protein Family: | Nicalin |
| UniProt Gene Name: | NCLN |
| UniProt Entry Name: | NCLN_HUMAN |