NCLN Antibody (PACO04789)
- SKU:
- PACO04789
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | NCLN Antibody |
| Antibody SKU: | PACO04789 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | WB:1:500-1:2000, IHC:1:100-1:300 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | synthesized peptide derived from the C-terminal region of human Nicalin. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | NCLN; Nicalin; Nicastrin-like protein |
| UniProt Protein Function: | NCLN: May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning. Belongs to the nicastrin family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 19p13.3Cellular Component: endoplasmic reticulum membrane; membrane; integral to membraneMolecular Function: protein bindingBiological Process: regulation of signal transduction |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q969V3 |
| NCBI GenInfo Identifier: | 51873031 |
| NCBI Gene ID: | 56926 |
| NCBI Accession: | NP_064555.2 |
| UniProt Secondary Accession: | Q969V3,O75252, Q6FI60, Q6ZMB7, Q8TAT7, Q96H48, Q96IS7 Q9BQH9, Q9BTX4, Q9NPP2 |
| UniProt Related Accession: | Q969V3 |
| Molecular Weight: | 62,974 Da |
| NCBI Full Name: | nicalin |
| NCBI Synonym Full Names: | nicalin |
| NCBI Official Symbol: | NCLN |
| NCBI Official Synonym Symbols: | NET59 |
| NCBI Protein Information: | nicalin; nicastrin-like protein; nicalin homolog (zebrefish) |
| UniProt Protein Name: | Nicalin |
| UniProt Synonym Protein Names: | Nicastrin-like protein |
| Protein Family: | Nicalin |
| UniProt Gene Name: | NCLN |
| UniProt Entry Name: | NCLN_HUMAN |
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