NCAPD3 Antibody (PACO15921)
- SKU:
- PACO15921
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | NCAPD3 Antibody (PACO15921) |
| Antibody SKU: | PACO15921 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Fusion protein of human NCAPD3 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO15921(NCAPD3 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using PACO15921(NCAPD3 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | Condensin complexes I and II play essential roles in mitotic chromosome assembly and segregation. Both condensins contain 2 invariant structural maintenance of chromosome (SMC) subunits, SMC2 and SMC4, but they contain different sets of non-SMC subunits. NCAPD3 is 1 of 3 non-SMC subunits that define condensin II. |
| Synonyms: | non-SMC condensin II complex, subunit D3 |
| UniProt Protein Function: | NCAPD3: Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis.Protein type: Cell cycle regulationChromosomal Location of Human Ortholog: 11q25Cellular Component: membrane; nucleoplasmMolecular Function: chromatin binding; methylated histone residue binding; protein bindingBiological Process: chromosome separation; meiotic chromosome condensation; mitotic chromosome condensation |
| UniProt Protein Details: | |
| NCBI Summary: | Condensin complexes I and II play essential roles in mitotic chromosome assembly and segregation. Both condensins contain 2 invariant structural maintenance of chromosome (SMC) subunits, SMC2 (MIM 605576) and SMC4 (MIM 605575), but they contain different sets of non-SMC subunits. NCAPD3 is 1 of 3 non-SMC subunits that define condensin II (Ono et al., 2003 [PubMed 14532007]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | P42695 |
| NCBI GenInfo Identifier: | 82654946 |
| NCBI Gene ID: | 23310 |
| NCBI Accession: | P42695.2 |
| UniProt Secondary Accession: | P42695,Q4KMQ9, A6NFS2 |
| UniProt Related Accession: | P42695 |
| Molecular Weight: | 168,891 Da |
| NCBI Full Name: | Condensin-2 complex subunit D3 |
| NCBI Synonym Full Names: | non-SMC condensin II complex subunit D3 |
| NCBI Official Symbol: | NCAPD3 |
| NCBI Official Synonym Symbols: | CAPD3; hcp-6; CAP-D3; hHCP-6; hCAP-D3 |
| NCBI Protein Information: | condensin-2 complex subunit D3 |
| UniProt Protein Name: | Condensin-2 complex subunit D3 |
| UniProt Synonym Protein Names: | Non-SMC condensin II complex subunit D3; hCAP-D3 |
| Protein Family: | Condensin-2 complex |
| UniProt Gene Name: | NCAPD3 |
| UniProt Entry Name: | CNDD3_HUMAN |
| Antibodies |
| NCAPD3 Antibody (PACO10752) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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