NCAM /CD56 Monoclonal Antibody
- SKU:
- CAB23300
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
Description
| Product Name: | NCAM /CD56 Monoclonal Antibody |
| Product Code: | CAB23300 |
| Reactivity: | Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC60182 |
| Reactivity: | Mouse, Rat |
| Tested Applications: | WB, IHC-P, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Recommended Dilution: | WB 1:500-1:1000, IHC-P 1:50-1:200, IF 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | Neuro-2a, Mouse brain, Rat brain |
| Cellular Location: | Cell membrane ; Single-pass type I membrane protein |
Predicted to enable LRR domain binding activity and phosphatase binding activity. Involved in commissural neuron axon guidance and regulation of semaphorin-plexin signaling pathway. Acts upstream of or within several processes, including homotypic cell-cell adhesion; positive regulation of calcium-mediated signaling; and regulation of exocyst assembly. Located in several cellular components, including external side of plasma membrane; growth cone; and neuronal cell body. Is expressed in several structures, including embryo mesenchyme; nervous system; sensory organ; skin; and urinary system. Human ortholog(s) of this gene implicated in bipolar disorder; middle cerebral artery infarction; and pancreatic cancer. Orthologous to human NCAM1 (neural cell adhesion molecule 1).
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-711 of mouse NCAM /CD56(NP_001106675.1). |
| Sequence: | LQVDI VPSQG EISVG ESKFF LCQVA GDAKD KDISW FSPNG EKLSP NQQRI SVVWN DDDSS TLTIY NANID DAGIY KCVVT AEDGT QSEAT VNVKI FQKLM FKNAP TPQEF KEGED AVIVC DVVSS LPPTI IWKHK GRDVI LKKDV RFIVL SNNYL QIRGI KKTDE GTYRC EGRIL ARGEI NFKDI QVIVN VPPTV QARQS IVNAT ANLGQ SVTLV CDADG FPEPT MSWTK DGEPI ENEEE DDEKH IFSDD SSELT IRNVD KNDEA EYVCI AENKA GEQDA SIHLK VFAKP KITYV ENQTA MELEE QVTLT CEASG DPIPS ITWRT STRNI SSEEK TLDGH MVVRS HARVS SLTLK SIQYT DAGEY ICTAS NTIGQ DSQSM YLEFQ YAPKL QGPVA VYTWE GNQVN ITCEV FAYPS ATISW FRDGQ LLPSS NYSNI KIYNT PSASY LEVTP DSEND FGNYN CTAVN RIGQE SLEFI LVQAD TPSSP SIDRV EPYSS TAQVQ FDEPE ATGGV PILKY KAEWK SLGEE SWHFK WYDAK EANME GIVTI MGLKP ETRYS VRLAA LNGKG LGEIS AATEF KTQPV REPSA PKLEG QMGED GNSIK VNLIK QDDGG SPIRH YLVKY RALAS EWKPE IRLPS GSDHV MLKSL DWNAE YEVYV VAENQ QGKSK AAHFV FRTSA QPTAI PANGS PTAGL ST |
| Synonyms: | CD56, Ncam, E-NCAM, NCAM-1 |
| Calculated MW: | 67kDa/80kDa/93kDa/119kDa |
| Observed MW: | 120-220kDa |
Related Products
NCAM Monoclonal Antibody
