NAPSA Polyclonal Antibody
- SKU:
- CAB24485
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | NAPSA Polyclonal Antibody |
| Product Code: | CAB24485 |
| Reactivity: | Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:1000-1:5000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | Rat lung |
| Cellular Location: | Secreted |
This gene encodes a member of the peptidase A1 family of aspartic proteases. The encoded preproprotein is proteolytically processed to generate an activation peptide and the mature protease. The activation peptides of aspartic proteinases function as inhibitors of the protease active site. These peptide segments, or pro-parts, are deemed important for correct folding, targeting, and control of the activation of aspartic proteinase zymogens. The encoded protease may play a role in the proteolytic processing of pulmonary surfactant protein B in the lung and may function in protein catabolism in the renal proximal tubules. This gene has been described as a marker for lung adenocarcinoma and renal cell carcinoma.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 64-190 of human NAPSA (NP_004842.1). |
| Sequence: | KPIFV PLSNY RDVQY FGEIG LGTPP QNFTV AFDTG SSNLW VPSRR CHFFS VPCWL HHRFD PKASS SFQAN GTKFA IQYGT GRVDG ILSED KLTIG GIKGA SVIFG EALWE PSLVF AFAHF DGILG LG |
| Synonyms: | NAPSA, KAP, Kdap, NAP1, NAPA, SNAPA, napsin-A |
| Calculated MW: | 45kDa |
| Observed MW: | 38-55kDa |
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