NAPEPLD Antibody (PACO37130)
- SKU:
- PACO37130
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | NAPEPLD Antibody (PACO37130) |
| Antibody SKU: | PACO37130 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Recombinant Human N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D protein (1-200AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot. All lanes: NAPEPLD antibody at 6µg/ml. Lane 1: Mouse large intestine tissue. Lane 2: Mouse kidney tissue. Lane 3: Mouse stomach tissue. Lane 4: MCF-7 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 46 kDa. Observed band size: 46 kDa. |
| Background: | Hydrolyzes N-acyl-phosphatidylethanolamines (NAPEs) to produce N-acylethanolamines (NAEs) and phosphatidic acid, Responsible for the generation of anandamide (N-arachidonoylethanolamine), the ligand of cannabinoid and vanilloid receptors. |
| Synonyms: | N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D (N-acyl phosphatidylethanolamine phospholipase D) (NAPE-PLD) (NAPE-hydrolyzing phospholipase D) (EC 3.1.4.54), NAPEPLD, C7orf18 |
| UniProt Protein Function: | NAPEPLD: Hydrolyzes N-acyl-phosphatidylethanolamines (NAPEs) to produce N-acylethanolamines (NAEs) and phosphatidic acid. Responsible for the generation of anandamide (N- arachidonoylethanolamine), the ligand of cannabinoid and vanilloid receptors. Belongs to the NAPE-PLD family.Protein type: EC 3.1.4.54; PhospholipaseChromosomal Location of Human Ortholog: 7q22.1Cellular Component: cytoplasmMolecular Function: zinc ion bindingBiological Process: phototransduction, visible light; phospholipid catabolic process; retinoid metabolic process |
| UniProt Protein Details: | |
| NCBI Summary: | NAPEPLD is a phospholipase D type enzyme that catalyzes the release of N-acylethanolamine (NAE) from N-acyl-phosphatidylethanolamine (NAPE) in the second step of the biosynthesis of N-acylethanolamine (Okamoto et al., 2004 [PubMed 14634025]).[supplied by OMIM, Oct 2008] |
| UniProt Code: | Q6IQ20 |
| NCBI GenInfo Identifier: | 170932481 |
| NCBI Gene ID: | 222236 |
| NCBI Accession: | NP_945341.3 |
| UniProt Secondary Accession: | Q6IQ20,Q5CZ87, Q769K1 |
| UniProt Related Accession: | Q6IQ20 |
| Molecular Weight: | 45,596 Da |
| NCBI Full Name: | N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D |
| NCBI Synonym Full Names: | N-acyl phosphatidylethanolamine phospholipase D |
| NCBI Official Symbol: | NAPEPLD |
| NCBI Official Synonym Symbols: | FMP30; NAPE-PLD |
| NCBI Protein Information: | N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D; NAPE-hydrolyzing phospholipase D |
| UniProt Protein Name: | N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D |
| UniProt Synonym Protein Names: | |
| Protein Family: | N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase |
| UniProt Gene Name: | NAPEPLD |
| UniProt Entry Name: | NAPEP_HUMAN |
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