Description
system_update_alt Datasheet
Product Name: | NANOG Antibody |
Product Sku: | CPAB0556 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human NANOG mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human NANOG amino acids 1-154 purified from Ecoli. |
Clone: | P5A10AT. |
Reactivity: | Other bodies |
Applications: | Western Blot, ELISA, Immunohistochemistry |
Purification Method: | NANOG antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. |
Isotype: | IgG2a |
Background: | NANOG is a multidomain homeobox transcription factor which functions to maintain the undifferentiated state of pluripotent stem cells. NANOG expression counteracts the differentiation-promoting signals induced by the extrinsic factors LIF, Stat3 and BMP. Once NANOG expression is downregulated, cell differentiation can proceed. Proteins which regulate NANOG expression include transcription factors Oct4, SOX2, FoxD3, and Tcf3 and tumor suppressor p53. |
Synonyms: | NANOG, Homeobox protein NANOG, Homeobox transcription factor Nanog, hNanog. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |