NADPH oxidase 4 (NOX4) Monoclonal Antibody (CAB22149)
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- SKU:
- CAB22149
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
Description
| Product Name: | NADPH oxidase 4 (NOX4) Monoclonal Antibody |
| Product Code: | CAB22149 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC55045 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Recommended Dilution: | WB 1:500-1:1000, IHC-P 1:50-1:200, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | HK-2, HUVEC |
| Cellular Location: | Cell junction, Cell membrane, Endoplasmic reticulum membrane, Multi-pass membrane protein, Nucleus, focal adhesion, nucleolus |
| Customer Validation: | WB(Homo sapiens) |
This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.
| Immunogen: | Recombinant protein of human NADPH oxidase 4 (NOX4) |
| Sequence: | LHNKF WQENR PDYVN IQLYL SQTDG IQKII GEKYH ALNSR LFIGR PRWKL LFDEI AKYNR GKTVG VFCCG PNSLS KTLHK LSNQN NSYGT RFEYN KESFS |
| Synonyms: | KOX, KOX-1, RENOX |
| Calculated MW: | 67KDa |
| Observed MW: | 62kDa |
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