NAALADL2 Antibody (PACO36230)
- SKU:
- PACO36230
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | NAALADL2 Antibody (PACO36230) |
| Antibody SKU: | PACO36230 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:2000-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Recombinant Human Inactive N-acetylated-alpha-linked acid, c dipeptidase-like protein 2 protein (143-795AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in: Mouse lung tissue, Mouse kidney tissue. All lanes: NAALADL2 antibody at 3.5µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 89, 37 kDa. Observed band size: 89 kDa. |
 | Immunohistochemistry of paraffin-embedded human placenta tissue using PACO36230 at dilution of 1:100. |
 | Immunofluorescent analysis of Hela cells using PACO36230 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | May be catalytically inactive. |
| Synonyms: | Inactive N-acetylated-alpha-linked acid, c dipeptidase-like protein 2 (NAALADase L2), NAALADL2 |
| UniProt Protein Function: | Function: May be catalytically inactive.Subcellular location: Membrane; Single-pass type II membrane protein Potential. Tissue specificity: Expressed at higher level in kidney and placenta. In embryo, it is mainly confined to duodenal and stomach endoderm, mesonephros, metanephros and pancreas.Miscellaneous: The gene maps to 3q26.31, a region associated with Cornelia de Lange syndrome. However, Ref.1 failed to identify specific mutations in a panel of DNA samples from patients with Cornelia de Lange syndrome.Sequence similarities: Belongs to the peptidase M28 family. M28B subfamily.Caution: Although related to the peptidase M28 family, it lacks the conserved zinc-binding and active sites and therefore has probably lost hydrolase activity.Sequence caution: The sequence CAE54974.2 differs from that shown. Reason: Contaminating sequence at the C-terminus.The sequence CAH56310.1 differs from that shown. Reason: Frameshift at positions 509 and 518. |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q58DX5 |
| NCBI GenInfo Identifier: | 34785667 |
| NCBI Gene ID: | 254827 |
| NCBI Accession: | AAH57243.1 |
| UniProt Secondary Accession: | Q58DX5 |
| UniProt Related Accession: | Q58DX5 |
| Molecular Weight: | |
| NCBI Full Name: | NAALADL2 protein |
| NCBI Synonym Full Names: | N-acetylated alpha-linked acidic dipeptidase like 2 |
| NCBI Official Symbol: | NAALADL2 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | inactive N-acetylated-alpha-linked acidic dipeptidase-like protein 2 |
| UniProt Protein Name: | Inactive N-acetylated-alpha-linked acidic dipeptidase-like protein 2 |
| UniProt Synonym Protein Names: | |
| Protein Family: | |
| UniProt Gene Name: | NAALADL2 |
| UniProt Entry Name: | NADL2_HUMAN |
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