N-Myc/MYCN Monoclonal Antibody (CAB22175)

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SKU:
CAB22175
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB

Description

Product Name:N-Myc/MYCN Monoclonal Antibody
Product Code:CAB22175
Reactivity:Mouse
Applications:Western blotting
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC55217
Reactivity:Mouse
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:1000-1:5000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Positive Samples:Neuro-2a
Cellular Location:Nucleus

This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human N-Myc/MYCN (NP_005369.2).
Sequence:MPSCS TSTMP GMICK NPDLE FDSLQ PCFYP DEDDF YFGGP DSTPP GEDIW KKFEL LPTPP LSPSR GFAEH SSEPP SWVTE MLLEN ELWGS PAEED AFGLG
Synonyms:NMYC, ODED, MODED, N-myc, bHLHe37, MYCNsORF, MYCNsPEP
Calculated MW:50kDa
Observed MW:60kDa
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