Description
Product Name: | MYH14 Monoclonal Antibody |
Product Code: | CAB21933 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting, Immunofluorescence |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC53864 |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, IF/ICC, ELISA |
Key Applications: | Western blotting, Immunofluorescence |
Recommended Dilution: | WB 1:1000-1:5000, IF/ICC 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | MCF7, Mouse lung, Rat lung |
Cellular Location: | cytosol, extracellular exosome, growth cone |
Customer Validation: | IF(Homo sapiens) |
This gene encodes a member of the myosin superfamily. The protein represents a conventional non-muscle myosin; it should not be confused with the unconventional myosin-14 (MYO14). Myosins are actin-dependent motor proteins with diverse functions including regulation of cytokinesis, cell motility, and cell polarity. Mutations in this gene result in one form of autosomal dominant hearing impairment. Multiple transcript variants encoding different isoforms have been found for this gene.
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 600-700 of human MYH14 (NP_079005.3). |
Sequence: | AGKVD YKANE WLMKN MDPLN DNVAA LLHQS TDRLT AEIWK DVEGI VGLEQ VSSLG DGPPG GRPRR GMFRT VGQLY KESLS RLMAT LSNTN PSFVR CIVPN H |
Synonyms: | DFNA4, MHC16, MYH17, PNMHH, DFNA4A, myosin, FP17425, NMHC II-C, NMHC-II-C |
Calculated MW: | 228kDa |
Observed MW: | 250kDa |