Myeloperoxidase (MPO) Monoclonal Antibody (CAB23937)

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SKU:
CAB23937
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
IHC

Description

Product Name:Myeloperoxidase (MPO) Monoclonal Antibody
Product Code:CAB23937
Reactivity:Human
Applications:Immunohistochemistry
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC53226
Reactivity:Human
Tested Applications:IHC-P, ELISA
Key Applications:Immunohistochemistry
Recommended Dilution:IHC-P 1:50-1:200
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Cellular Location:azurophil granule, extracellular exosome, extracellular region, extracellular space, lysosome, nucleoplasm, nucleus, phagocytic vesicle lumen

Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils.

Immunogen:A synthetic peptide corresponding to a sequence within amino acids 646-745 of human Myeloperoxidase (MPO) (NP_000241.1).
Sequence:GVSEP LKRKG RVGPL LACII GTQFR KLRDG DRFWW ENEGV FSMQQ RQALA QISLP RIICD NTGIT TVSKN NIFMS NSYPR DFVNC STLPA LNLAS WREAS
Calculated MW:84kDa
Observed MW:Refer to figures
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