Description
system_update_alt Datasheet
| Product Name: | Myc Antibody |
| Product Sku: | CPAB0736 |
| Size: | 100μl |
| Host Species: | |
| Immunogen: | |
| Clone: | PPMYCSHG. |
| Reactivity: | Other Polyclonal bodies |
| Applications: | Western Blot |
| Purification Method: | |
| Isotype: | |
| Background: | c-Myc is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of c-Myc have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. |
| Synonyms: | MYC, CMYC, C-MYS, V-MYC, P64. |
| Storage Buffer: |