Myc Monoclonal Antibody [PPMYCSHG] (CPAB0736)

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SKU:
CPAB0736
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Clone:
PPMYCSHG
Applications:
WB

Description

system_update_alt Datasheet
Product Name:Myc Antibody
Product Sku:CPAB0736
Size:100μl
Host Species:
Immunogen:
Clone:PPMYCSHG.
Reactivity:Other Polyclonal bodies
Applications:Western Blot
Purification Method:
Isotype:
Background:c-Myc is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of c-Myc have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.
Synonyms:MYC, CMYC, C-MYS, V-MYC, P64.
Storage Buffer:
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