Description
system_update_alt Datasheet
Product Name: | Myc-HRP Antibody |
Product Sku: | CPAB0488 |
Size: | 100μl |
Host Species: | Mouse |
Immunogen: | |
Clone: | PMYCHRPSHG. |
Reactivity: | Other bodies |
Applications: | Western Blot |
Purification Method: | |
Isotype: | IgG1 |
Background: | c-Myc is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of c-Myc have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. |
Synonyms: | MYC, CMYC, C-MYS, V-MYC, P64. |
Storage Buffer: |