Description
| Antibody Name: | Mybpc3 Antibody (PACO28450) |
| Antibody SKU: | PACO28450 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Rat |
| Immunogen: | Recombinant Rat Myosin-binding protein C, cardiac-type protein (645-864AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role. |
| Synonyms: | Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform), Mybpc3 |
| UniProt Protein Function: | MYBPC3: Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role. Belongs to the immunoglobulin superfamily. MyBP family.Protein type: Myosin-bindingChromosomal Location of Human Ortholog: 3q24Cellular Component: A band; M band; myofibril; sarcomere; striated muscle thick filament; Z discMolecular Function: actin filament binding; identical protein binding; muscle alpha-actinin binding; myosin binding; myosin heavy chain binding; structural constituent of muscleBiological Process: actin filament organization; cardiac muscle contraction; heart morphogenesis; muscle contraction; myosin filament assembly; regulation of heart contraction; regulation of heart rate; regulation of striated muscle contraction; sarcomere organization; ventricular cardiac muscle morphogenesis |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P56741 |
| NCBI GenInfo Identifier: | 157824043 |
| NCBI Gene ID: | 295929 |
| NCBI Accession: | NP_001099960.1 |
| UniProt Secondary Accession: | P56741 |
| UniProt Related Accession: | P56741 |
| Molecular Weight: | 26.1kD |
| NCBI Full Name: | myosin-binding protein C, cardiac-type |
| NCBI Synonym Full Names: | myosin binding protein C, cardiac |
| NCBI Official Symbol: | Mybpc3 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | myosin-binding protein C, cardiac-type |
| UniProt Protein Name: | Myosin-binding protein C, cardiac-type |
| UniProt Synonym Protein Names: | C-protein, cardiac muscle isoform |
| Protein Family: | Myosin-binding protein |
| UniProt Gene Name: | Mybpc3 |
| UniProt Entry Name: |