MYBL2 Antibody (PACO02919)
- SKU:
- PACO02919
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | MYBL2 Antibody |
| Antibody SKU: | PACO02919 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IF |
| Recommended Dilutions: | WB:1:500-1:2000, IF:1:200-1:1000 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | synthesized peptide derived from human B-Myb around the non-phosphorylation site of S577. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | MYBL2; BMYB; Myb-related protein B; B-Myb; Myb-like protein 2 |
| UniProt Protein Function: | B-Myb: a transcription factor involved in cell cycle progression. Phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Transcript variants may exist for this gene, but their full-length natures have not been determined. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; DNA-binding; Transcription factor Chromosomal Location of Human Ortholog: 20q13.1 Cellular Component: nucleoplasm Molecular Function:protein binding; chromatin binding; transcription factor activity Biological Process: transcription, DNA-dependent; regulation of cell cycle; positive regulation of transcription from RNA polymerase II promoter; mitotic cell cycle; G2/M transition of mitotic cell cycle |
| NCBI Summary: | The protein encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2013] |
| UniProt Code: | P10244 |
| NCBI GenInfo Identifier: | 127584 |
| NCBI Gene ID: | 4605 |
| NCBI Accession: | P10244.1 |
| UniProt Secondary Accession: | P10244,Q53F07, B2RBS5, B7Z8D9, F8W6N6, |
| UniProt Related Accession: | P10244 |
| Molecular Weight: | 75,865 Da |
| NCBI Full Name: | Myb-related protein B |
| NCBI Synonym Full Names: | v-myb avian myeloblastosis viral oncogene homolog-like 2 |
| NCBI Official Symbol: | MYBL2 |
| NCBI Official Synonym Symbols: | BMYB; B-MYB |
| NCBI Protein Information: | myb-related protein B; myb-like protein 2; v-myb myeloblastosis viral oncogene homolog-like 2 |
| UniProt Protein Name: | Myb-related protein B |
| UniProt Synonym Protein Names: | Myb-like protein 2 |
| Protein Family: | Myb-related protein |
| UniProt Gene Name: | MYBL2 |
| UniProt Entry Name: | MYBB_HUMAN |
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