MYB Transcription Factor Activity Assay
- SKU:
- TFAB00135
- Product Type:
- ELISA Kit
- ELISA Type:
- Transcription Factor Assay
- Analytes:
- MYB
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
Description
| Product Name: | MYB Transcription Factor Activity Assay |
| Product Code: | TFAB00135 |
| Target: | MYB |
| Synonyms: | Proto-oncogene c-Myb |
| Reactivity: | Human, Mouse, Rat |
| Sample Types: | Nuclear or cell lysates |
The Assay Genie MYB transcription factor activity assay allows for the detection and qualitative analysis of endogenous levels of activated transcription factors in a variety of nuclear and cell lysates
Assay Genie ELISA kits are designed to significantly reduce experiment time and ensure sensitivity and flexibility for high-throughput screening.
| Assay Time: | 4.5 hours |
| Detection Method: | Colorimetric 450 nm |
| Size: | 12 x 8-Well Microstrips |
| Storage: | 4°C for 6 months |
| UniProt Protein Function: | Myb: Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells. 6 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:DNA-binding; Transcription factor; Oncoprotein Chromosomal Location of Human Ortholog: 6q22-q23 Molecular Function:protein binding Biological Process: chromatin remodeling; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; positive regulation of histone H3-K4 methylation; positive regulation of histone H3-K9 methylation; positive regulation of T-helper cell differentiation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent |
| NCBI Summary: | This gene encodes a protein with three HTH DNA-binding domains that functions as a transcription regulator. This protein plays an essential role in the regulation of hematopoiesis. This gene may be aberrently expressed or rearranged or undergo translocation in leukemias and lymphomas, and is considered to be an oncogene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016] |
| UniProt Code: | P10242 |
| NCBI GenInfo Identifier: | 2815504 |
| NCBI Gene ID: | 4602 |
| NCBI Accession: | P10242.2 |
| UniProt Secondary Accession: | P10242,P78391, P78392, P78525, P78526, Q14023, Q14024 E9PI07, E9PLZ5, E9PNA4, E9PNL6, E9PRS2, |
| UniProt Related Accession: | P10242 |
| Molecular Weight: | 37,507 Da |
| NCBI Full Name: | Transcriptional activator Myb |
| NCBI Synonym Full Names: | MYB proto-oncogene, transcription factor |
| NCBI Official Symbol: | MYB |
| NCBI Official Synonym Symbols: | efg; Cmyb; c-myb; c-myb_CDS |
| NCBI Protein Information: | transcriptional activator Myb |
| UniProt Protein Name: | Transcriptional activator Myb |
| UniProt Synonym Protein Names: | Proto-oncogene c-Myb |
| Protein Family: | Myb protein |
| UniProt Gene Name: | MYB |
| UniProt Entry Name: | MYB_HUMAN |
