MVK Monoclonal Antibody [PAT14F6A] (CPAB0175)
![MVK Monoclonal Antibody [PAT14F6A] (CPAB0175)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/608x608/products/58401/63583/mvk-monoclonal-antibody-pat14f6a-cpab0175__55976__01306.1706534998.jpg?c=1 "MVK Monoclonal Antibody [PAT14F6A] (CPAB0175)")
- SKU:
- CPAB0175
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Mouse
- Isotype:
- IgG3
- Clone:
- PAT14F6A
- Applications:
- WB
- Applications:
- ELISA
![MVK Monoclonal Antibody [PAT14F6A] (CPAB0175)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/1280x1280/products/58401/63583/mvk-monoclonal-antibody-pat14f6a-cpab0175__55976__01306.1706534998.jpg?c=1&imbypass=on "MVK Monoclonal Antibody [PAT14F6A] (CPAB0175)")
Description
system_update_alt Datasheet
| Product Name: | MVK Antibody |
| Product Sku: | CPAB0175 |
| Size: | 5μg |
| Host Species: | Mouse |
| Immunogen: | Anti-human MVK mAb, clone PAT14F6A, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human MVK protein 1-396 amino acids purified from Ecoli. |
| Clone: | PAT14F6A. |
| Reactivity: | Human |
| Applications: | Western Blot, ELISA |
| Purification Method: | MVK antibody was purified by protein-A affinity chromatography. |
| Isotype: | IgG3 |
| Background: | MVK is a member of the GHMP kinase family. Mevalonate is a vital mediator, and MVK an important early enzyme, in isoprenoid and sterol synthesis. MVK deficiency can result in gene mutation associated with Mevalonic aciduria, an illness which causes psychomotor retardation, failure to thrive hepatosplenomegaly, anemia and frequent febrile crises. Mutations in this gene also cause hyperimmunoglobulinaemia D and sporadic fever syndrome, in which the person suffers from recurrent episodes of fever related with lymphadenopathy, skin rash, gastrointestinal dismay and arthralgia. |
| Synonyms: | Mevalonate Kinase (Mevalonic Aciduria), LH Receptor MRNA-Binding Protein, LRBP, Mevalonate Kinase 1, MK, MVLK, EC 2.7.1.36. |
| Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |
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