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MVK Monoclonal Antibody [PAT14F6A] (CPAB0175)

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SKU CPAB0175
Product Type Antibody
Antibody Type Monoclonal Antibody
Reactivity Human
Host Species Mouse
Isotype IgG3
Clone PAT14F6A
Applications WB
Applications ELISA
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Description

system_update_alt Datasheet
Product Name:MVK Antibody
Product Sku:CPAB0175
Size:5μg
Host Species:Mouse
Immunogen:Anti-human MVK mAb, clone PAT14F6A, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human MVK protein 1-396 amino acids  purified from Ecoli.
Clone:PAT14F6A.
Reactivity:Human
Applications:Western Blot, ELISA
Purification Method:MVK antibody was purified by protein-A affinity chromatography.
Isotype:IgG3
Background:MVK is a member of the GHMP kinase family. Mevalonate is a vital mediator, and MVK an important early enzyme, in isoprenoid and sterol synthesis. MVK deficiency can result in gene mutation associated with Mevalonic aciduria, an illness which causes psychomotor retardation, failure to thrive hepatosplenomegaly, anemia and frequent febrile crises. Mutations in this gene also cause hyperimmunoglobulinaemia D and sporadic fever syndrome, in which the person suffers from recurrent episodes of fever related with lymphadenopathy, skin rash, gastrointestinal dismay and arthralgia.
Synonyms:Mevalonate Kinase (Mevalonic Aciduria), LH Receptor MRNA-Binding Protein, LRBP, Mevalonate Kinase 1, MK, MVLK, EC 2.7.1.36.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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