UniProt Protein Function: | MUM1: Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage. Belongs to the MUM1 family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Cell surface Chromosomal Location of Human Ortholog: 19p13.3 Cellular Component: cytoplasm; nucleus Molecular Function:nucleosome binding; protein binding Biological Process: DNA repair; establishment and/or maintenance of chromatin architecture |
UniProt Code: | Q2TAK8 |
NCBI GenInfo Identifier: | 259016340 |
NCBI Gene ID: | 84939 |
NCBI Accession: | Q2TAK8.3 |
UniProt Related Accession: | Q2TAK8 |
Molecular Weight: | 78.6kDa |
NCBI Full Name: | PWWP domain-containing DNA repair factor 3A |
NCBI Synonym Full Names: | PWWP domain containing 3A, DNA repair factor |
NCBI Official Symbol: | PWWP3A |
NCBI Official Synonym Symbols: | MUM1; MUM-1; EXPAND1; HSPC211 |
NCBI Protein Information: | PWWP domain-containing DNA repair factor 3A |
UniProt Protein Name: | PWWP domain-containing protein MUM1 |
UniProt Synonym Protein Names: | Mutated melanoma-associated antigen 1; MUM-1; Protein expandere |
Protein Family: | PWWP domain-containing protein |
UniProt Gene Name: | MUM1 |