Description
| Antibody Name: | MTMR12 Antibody (PACO10644) |
| Antibody SKU: | PACO10644 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human MTMR12 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | myotubularin related protein 12;MTMR12;3-PAP;PIP3AP ; |
| UniProt Protein Function: | MTMR12: Catalytically inactive phosphatase that plays a role as an adapter for the phosphatase myotubularin to regulate myotubularin intracellular location. Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Adaptor/scaffold; Protein phosphatase, tyrosine (non-receptor)Chromosomal Location of Human Ortholog: 5p13.3Cellular Component: cytoplasmMolecular Function: protein binding; phosphoric monoester hydrolase activityBiological Process: dephosphorylation |
| UniProt Protein Details: | |
| NCBI Summary: | Phosphatidylinositide 3-kinase-derived membrane-anchored phosphatidylinositides, such as phosphatidylinositol 3-phosphate (PtdIns(3)P), regulate diverse cellular processes. The protein encoded by this gene functions as an adaptor subunit in a complex with an active PtdIns(3)P 3-phosphatase. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014] |
| UniProt Code: | Q9C0I1 |
| NCBI GenInfo Identifier: | 94721263 |
| NCBI Gene ID: | 54545 |
| NCBI Accession: | NP_001035536.1 |
| UniProt Secondary Accession: | Q9C0I1,Q69YJ4, Q6PFW3, Q96QU2, Q9NX27 |
| UniProt Related Accession: | Q9C0I1 |
| Molecular Weight: | 86,148 Da |
| NCBI Full Name: | myotubularin-related protein 12 isoform 1 |
| NCBI Synonym Full Names: | myotubularin related protein 12 |
| NCBI Official Symbol: | MTMR12 |
| NCBI Official Synonym Symbols: | 3-PAP; PIP3AP |
| NCBI Protein Information: | myotubularin-related protein 12; 3-phosphatase adapter protein; 3-phosphatase adapter subunit; phosphatidylinositol-3-phosphate associated protein; phosphatidylinositol 3 phosphate 3-phosphatase adapter subunit; phosphatidylinositol-3 phosphate 3-phosphatase adapter subunit; phosphatidylinositol-3 phosphate 3-phosphatase adaptor subunit |
| UniProt Protein Name: | Myotubularin-related protein 12 |
| UniProt Synonym Protein Names: | Phosphatidylinositol 3 phosphate 3-phosphatase adapter subunit; 3-PAP; 3-phosphatase adapter protein |
| Protein Family: | Myotubularin-related protein |
| UniProt Gene Name: | MTMR12 |
| UniProt Entry Name: | MTMRC_HUMAN |