MTHFR Monoclonal Antibody
- SKU:
- CAB24013
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IF
Description
| Product Name: | MTHFR Monoclonal Antibody |
| Product Code: | CAB24013 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC63050 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunofluorescence |
| Recommended Dilution: | WB 1:1000-1:5000, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | Jurkat, Rat kidney |
| Cellular Location: | Cytosol, Synapse |
The protein encoded by this gene catalyzes the conversion of 5, 10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 363-656 of human MTHFR(NP_005948.3). |
| Sequence: | RPIFW ASRPK SYIYR TQEWD EFPNG RWGNS SSPAF GELKD YYLFY LKSKS PKEEL LKMWG EELTS EESVF EVFVL YLSGE PNRNG HKVTC LPWND EPLAA ETSLL KEELL RVNRQ GILTI NSQPN INGKP SSDPI VGWGP SGGYV FQKAY LEFFT SRETA EALLQ VLKKY ELRVN YHLVN VKGEN ITNAP ELQPN AVTWG IFPGR EIIQP TVVDP VSFMF WKDEA FALWI ERWGK LYEEE SPSRT IIQYI HDNYF LVNLV DNDFP LDNCL WQVVE DTLEL LNRPT QNARE TEAP |
| Synonyms: | MTHFR |
| Calculated MW: | 75kDa |
| Observed MW: | 70kDa |
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