Description
| Antibody Name: | MTHFD2L Antibody (PACO41106) |
| Antibody SKU: | PACO41106 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Recombinant Human Probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 protein (136-268AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
![]() | Western blot. All lanes: MTHFD2L antibody at 6µg/ml + Mouse lung tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 38, 32, 8, 25, 33 kDa. Observed band size: 14 kDa. |
| Background: | mitochondrion, methenyltetrahydrofolate cyclohydrolase activity, methylenetetrahydrofolate dehydrogenase (NAD+) activity, methylenetetrahydrofolate dehydrogenase (NADP+) activity, one-carbon metabolic process |
| Synonyms: | Probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 (NADP-dependent methylenetetrahydrofolate dehydrogenase 2-like protein) (MTHFD2-like) [Includes: NAD-dependent methylenetetrahydrofolate dehydrogenase (EC 1.5.1.15); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)], MTHFD2L |
| UniProt Protein Function: | MTHFD2L: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family. 5 isoforms of the human protein are produced by alternative splicing.Protein type: EC 1.5.1.15; EC 3.5.4.9; Hydrolase; Mitochondrial; OxidoreductaseChromosomal Location of Human Ortholog: 4q13.3Cellular Component: cytosol; mitochondrial inner membrane; mitochondrial matrix; mitochondrionMolecular Function: methenyltetrahydrofolate cyclohydrolase activity; methylenetetrahydrofolate dehydrogenase (NAD+) activity; methylenetetrahydrofolate dehydrogenase (NADP+) activityBiological Process: 10-formyltetrahydrofolate metabolic process; folic acid metabolic process; histidine biosynthetic process; methionine biosynthetic process; one-carbon metabolic process; purine nucleotide biosynthetic process |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9H903 |
| NCBI GenInfo Identifier: | 222418558 |
| NCBI Gene ID: | 441024 |
| NCBI Accession: | NP_001138450.1 |
| UniProt Secondary Accession: | Q9H903,Q6P079, Q8N560 |
| UniProt Related Accession: | Q9H903 |
| Molecular Weight: | 32,891 Da |
| NCBI Full Name: | probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform 2 |
| NCBI Synonym Full Names: | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like |
| NCBI Official Symbol: | MTHFD2L |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 |
| UniProt Protein Name: | Probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 |
| UniProt Synonym Protein Names: | NADP-dependent methylenetetrahydrofolate dehydrogenase 2-like protein; MTHFD2-like |
| Protein Family: | Probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase |
| UniProt Gene Name: | MTHFD2L |
| UniProt Entry Name: |
