Name: MT1A Antibody (PACO33828)
SKU: PACO33828
Availability: OutOfStock

Antibody Name:	MT1A Antibody (PACO33828)
Antibody SKU:	PACO33828
Size:	50ug
Host Species:	Rabbit
Tested Applications:	ELISA, IHC
Recommended Dilutions:	ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:	Human
Immunogen:	Recombinant Human Metallothionein-1A protein (1-59AA)

Form:	Liquid
Storage Buffer:	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:	>95%, Protein G purified
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

	Immunohistochemistry of paraffin-embedded human prostate tissue using PACO33828 at dilution of 1:100.
	Immunohistochemistry of paraffin-embedded human small intestine tissue using PACO33828 at dilution of 1:100.
	Immunohistochemistry of paraffin-embedded human kidney tissue using PACO33828 at dilution of 1:100.

Background:	Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.
Synonyms:	Metallothionein-1A (MT-1A) (Metallothionein-IA) (MT-IA), MT1A, MT1S

UniProt Protein Function:	Function: Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.
UniProt Protein Details:	Subunit structure: Monomer. Domain: Class I metallothioneins contain 2 metal-binding domains: four divalent ions are chelated within cluster A of the alpha domain and are coordinated via cysteinyl thiolate bridges to 11 cysteine ligands. Cluster B, the corresponding region within the beta domain, can ligate three divalent ions to 9 cysteines. Sequence similarities: Belongs to the metallothionein superfamily. Type 1 family.
UniProt Code:	P04731
NCBI GenInfo Identifier:	269849625
NCBI Gene ID:	4489
NCBI Accession:	P04731.2
UniProt Secondary Accession:	P04731,Q86YX5,
UniProt Related Accession:	P04731
Molecular Weight:
NCBI Full Name:	Metallothionein-1A
NCBI Synonym Full Names:	metallothionein 1A
NCBI Official Symbol:	MT1A
NCBI Official Synonym Symbols:	MT1; MTC; MT1S
NCBI Protein Information:	metallothionein-1A; MT-1A; MT-IA; metallothionein 1S; metallothionein-IA; metallothionein 1A (functional)
UniProt Protein Name:	Metallothionein-1A
UniProt Synonym Protein Names:	Metallothionein-IA
Protein Family:	Metallothionein
UniProt Gene Name:	MT1A
UniProt Entry Name:	MT1A_HUMAN