Description
Product Name: | MST1/MST1/MST1/MST1/STK4 Polyclonal Antibody |
Product Code: | CAB21842 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, IHC-P, IF/ICC, ELISA |
Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
Recommended Dilution: | WB 1:500-1:1000, IHC-P 1:50-1:100, IF/ICC 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Positive Samples: | HeLa, Mouse lung |
Cellular Location: | Cytoplasm, Nucleus |
The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 303-487 of human MST1/MST1/MST1/MST1/STK4 (NP_006273.1). |
Sequence: | KRQES QQREV DQDDE ENSEE DEMDS GTMVR AVGDE MGTVR VASTM TDGAN TMIEH DDTLP SQLGT MVINA EDEEE EGTMK RRDET MQPAK PSFLE YFEQK EKENQ INSFG KSVPG PLKNS SDWKI PQDGD YEFLK SWTVE DLQKR LLALD PMMEQ EIEEI RQKYQ SKRQP ILDAI EAKKR RQQNF |
Synonyms: | KRS2, MST1, YSK3 |
Calculated MW: | 56kDa |
Observed MW: | 56kDa |