MSI1 Antibody (PACO20824)
- SKU:
- PACO20824
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | MSI1 Antibody (PACO20824) |
| Antibody SKU: | PACO20824 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Synthetic peptide of human MSI1 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO20824(MSI1 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | Gel: 12%SDS-PAGE,Lysate: 40 μgPrimary antibody: PACO20824(MSI1 Antibody) at dilution 1/200 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 5 minutes. |
 | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO20824(MSI1 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | This gene encodes a protein containing two conserved tandem RNA recognition motifs. Similar proteins in other species function as RNA-binding proteins and play central roles in posttranscriptional gene regulation. Expression of this gene has been correlated with the grade of the malignancy and proliferative activity in gliomas and melanomas. A pseudogene for this gene is located on chromosome 11q13. |
| Synonyms: | musashi RNA-binding protein 1 |
| UniProt Protein Function: | Musashi-1: RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'- GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'- [GA]U(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system. Detected in fetal kidney, brain, liver and lung, and in adult brain and pancreas. Detected in hepatoma cell lines. Belongs to the Musashi family. |
| UniProt Protein Details: | Protein type:RNA-binding Chromosomal Location of Human Ortholog: 12q24 Molecular Function:RNA binding Biological Process: nervous system development |
| NCBI Summary: | This gene encodes a protein containing two conserved tandem RNA recognition motifs. Similar proteins in other species function as RNA-binding proteins and play central roles in posttranscriptional gene regulation. Expression of this gene has been correlated with the grade of the malignancy and proliferative activity in gliomas and melanomas. A pseudogene for this gene is located on chromosome 11q13. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O43347 |
| NCBI GenInfo Identifier: | 51316193 |
| NCBI Gene ID: | 4440 |
| NCBI Accession: | O43347.1 |
| UniProt Secondary Accession: | O43347,Q96PU0, Q96PU1, Q96PU2, Q96PU3, |
| UniProt Related Accession: | O43347 |
| Molecular Weight: | 39,125 Da |
| NCBI Full Name: | RNA-binding protein Musashi homolog 1 |
| NCBI Synonym Full Names: | musashi RNA binding protein 1 |
| NCBI Official Symbol: | MSI1 |
| NCBI Protein Information: | RNA-binding protein Musashi homolog 1 |
| UniProt Protein Name: | RNA-binding protein Musashi homolog 1 |
| Protein Family: | RNA-binding protein |
| UniProt Gene Name: | MSI1 |
| UniProt Entry Name: | MSI1H_HUMAN |
| Antibodies |
| Anti-MSI1 Antibody (CAB2609) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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