Description
Antibody Name: | MRPS5 Antibody (PACO22421) |
Antibody SKU: | PACO22421 |
Size: | 100ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:50-1:100 |
Species Reactivity: | Human |
Immunogen: | Synthesized peptide derived from internal of human MRPS5. |
Form: | Liquid |
Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry analysis of paraffin-embedded human testis tissue using MRPS5 antibody. |
Background: | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S5P family. Pseudogenes corresponding to this gene are found on chromosomes 4q, 5q, and 18q. |
Synonyms: | Mitochondrial 28S ribosomal protein S5; S5mt; MRP-S5; |
UniProt Protein Function: | MRPS5: a mitochondrial ribosomal protein encoded by a nuclear gene that helps in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S5P family. Pseudogenes corresponding to this gene are found on chromosomes 4q, 5q, and 18q. [provided by RefSeq, Jul 2008]Protein type: RNA-bindingChromosomal Location of Human Ortholog: 2p11.2-q11.2Cellular Component: mitochondrion; mitochondrial small ribosomal subunit; mitochondrial inner membraneMolecular Function: structural constituent of ribosomeBiological Process: mitochondrial translation; translation; organelle organization and biogenesis |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | P82675 |
NCBI GenInfo Identifier: | 13994259 |
NCBI Gene ID: | 64969 |
NCBI Accession: | NP_114108 |
UniProt Secondary Accession: | P82675 |
UniProt Related Accession: | P82675 |
Molecular Weight: | 47kDa |
NCBI Full Name: | |
NCBI Synonym Full Names: | |
NCBI Official Symbol: | |
NCBI Official Synonym Symbols: | |
NCBI Protein Information: | |
UniProt Protein Name: | 28S ribosomal protein S5, mitochondrial |
UniProt Synonym Protein Names: | |
Protein Family: | 28S ribosomal protein |
UniProt Gene Name: | MRPS5 |
UniProt Entry Name: | RT05_HUMAN |
Antibodies |
MRPS5 Antibody (PACO05068) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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