MRPS34 Antibody (PACO22420)
- SKU:
- PACO22420
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | MRPS34 Antibody (PACO22420) |
| Antibody SKU: | PACO22420 |
| Size: | 100ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthesized peptide derived from C-terminal of human MRPS34. |
| Form: | Liquid |
| Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot analysis of extracts from HeLa cells, HUVEC cells, HT-29 cells, A549 cells and Jurkat cells, using MRPS34 antibody. |
| Background: | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. Alternative splicing results in multiple transcript variants. |
| Synonyms: | mitochondrial 28S ribosomal protein S34; mitochondrial ribosomal protein S34; MRP-S12; MRP-S34; RT34 |
| UniProt Protein Function: | MRPS34: Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins.Chromosomal Location of Human Ortholog: 16p13.3Cellular Component: mitochondrial inner membrane; mitochondrionBiological Process: mitochondrial translation |
| UniProt Protein Details: | |
| NCBI Summary: | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] |
| UniProt Code: | P82930 |
| NCBI GenInfo Identifier: | 24212369 |
| NCBI Gene ID: | 65993 |
| NCBI Accession: | P82930.2 |
| UniProt Secondary Accession: | P82930,Q9BVI7 |
| UniProt Related Accession: | P82930 |
| Molecular Weight: | 25,650 Da |
| NCBI Full Name: | 28S ribosomal protein S34, mitochondrial |
| NCBI Synonym Full Names: | mitochondrial ribosomal protein S34 |
| NCBI Official Symbol: | MRPS34 |
| NCBI Official Synonym Symbols: | MRPS12; MRP-S12; MRP-S34 |
| NCBI Protein Information: | 28S ribosomal protein S34, mitochondrial |
| UniProt Protein Name: | 28S ribosomal protein S34, mitochondrial |
| UniProt Synonym Protein Names: | |
| Protein Family: | 28S ribosomal protein |
| UniProt Gene Name: | MRPS34 |
| UniProt Entry Name: | RT34_HUMAN |
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