MRPL50 Antibody (PACO38798)
- SKU:
- PACO38798
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | MRPL50 Antibody (PACO38798) |
| Antibody SKU: | PACO38798 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human 39S ribosomal protein L50, mitochondrial protein (1-158AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human lung tissue using PACO38798 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human ovarian cancer using PACO38798 at dilution of 1:100. |
| Background: | mitochondrial inner membrane, mitochondrial translation, mitochondrial translational elongation, mitochondrial translational initiation, mitochondrial translational termination, organelle organization |
| Synonyms: | 39S ribosomal protein L50, mitochondrial (L50mt) (MRP-L50) (Mitochondrial large ribosomal subunit protein mL50), MRPL50 |
| UniProt Protein Function: | MRPL50: 2 isoforms of the human protein are produced by alternative splicingChromosomal Location of Human Ortholog: 9q31.1Cellular Component: mitochondrial inner membrane |
| UniProt Protein Details: | |
| NCBI Summary: | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a putative 39S subunit protein and belongs to the L47P ribosomal protein family. Pseudogenes corresponding to this gene are found on chromosomes 2p, 2q, 5p, and 10q. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q8N5N7 |
| NCBI GenInfo Identifier: | 118573685 |
| NCBI Gene ID: | 54534 |
| NCBI Accession: | Q8N5N7.2 |
| UniProt Secondary Accession: | Q8N5N7,Q5T7E0, Q9NX15, B7Z358 |
| UniProt Related Accession: | Q8N5N7 |
| Molecular Weight: | 15,524 Da |
| NCBI Full Name: | 39S ribosomal protein L50, mitochondrial |
| NCBI Synonym Full Names: | mitochondrial ribosomal protein L50 |
| NCBI Official Symbol: | MRPL50 |
| NCBI Official Synonym Symbols: | MRP-L50 |
| NCBI Protein Information: | 39S ribosomal protein L50, mitochondrial |
| UniProt Protein Name: | 39S ribosomal protein L50, mitochondrial |
| UniProt Synonym Protein Names: | |
| Protein Family: | 39S ribosomal protein |
| UniProt Gene Name: | MRPL50 |
| UniProt Entry Name: | RM50_HUMAN |
| Antibodies |
| MRPL50 Antibody (PACO01103) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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