MRPL35 Antibody (PACO07202)
- SKU:
- PACO07202
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | MRPL35 Antibody (PACO07202) |
| Antibody SKU: | PACO07202 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:10000, WB:1:500-1:2000 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthesized peptide derived from the Internal region of human MRP-L35. at AA rangle: 80-160 |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot analysis of 293 using MRP-L35 antibody. Antibody was diluted at 1:2000. Secondary antibody was diluted at 1:20000. |
 | Western blot analysis of 293T COLO using MRP-L35 antibody. Antibody was diluted at 1:2000. Secondary antibody was diluted at 1:20000. |
| Synonyms: | MRPL35; BM-007; 39S ribosomal protein L35, mitochondrial; L35mt; MRP-L35 |
| UniProt Protein Function: | MRPL35: a mitochondrial ribosomal protein encoded by a nuclear gene that helps in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Sequence analysis identified three transcript variants. Pseudogenes corresponding to this gene are found on chromosomes 6p, 10q, and Xp. [provided by RefSeq, Jul 2008]Protein type: Translation; MitochondrialChromosomal Location of Human Ortholog: 2p11.2Cellular Component: mitochondrial inner membrane; mitochondrial ribosome; mitochondrionMolecular Function: structural constituent of ribosomeBiological Process: mitochondrial translation; organelle organization and biogenesis; translation |
| UniProt Protein Details: | |
| NCBI Summary: | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Sequence analysis identified three transcript variants. Pseudogenes corresponding to this gene are found on chromosomes 6p, 10q, and Xp. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9NZE8 |
| NCBI GenInfo Identifier: | 124028627 |
| NCBI Gene ID: | 51318 |
| NCBI Accession: | Q9NZE8.3 |
| UniProt Secondary Accession: | Q9NZE8,Q658U7, Q8WWA2, A6NKV6, B2RB93 |
| UniProt Related Accession: | Q9NZE8 |
| Molecular Weight: | 19,192 Da |
| NCBI Full Name: | 39S ribosomal protein L35, mitochondrial |
| NCBI Synonym Full Names: | mitochondrial ribosomal protein L35 |
| NCBI Official Symbol: | MRPL35 |
| NCBI Official Synonym Symbols: | L35mt; MRP-L35 |
| NCBI Protein Information: | 39S ribosomal protein L35, mitochondrial |
| UniProt Protein Name: | 39S ribosomal protein L35, mitochondrial |
| UniProt Synonym Protein Names: | |
| Protein Family: | 39S ribosomal protein |
| UniProt Gene Name: | MRPL35 |
| UniProt Entry Name: | RM35_HUMAN |
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