Description
| Antibody Name: | MRPL20 Antibody (PACO40510) |
| Antibody SKU: | PACO40510 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human 39S ribosomal protein L20, mitochondrial protein (46-149AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human skin tissue using PACO40510 at dilution of 1:100. |
| Synonyms: | 39S ribosomal protein L20, mitochondrial (L20mt) (MRP-L20) (Mitochondrial large ribosomal subunit protein bL20m), MRPL20 |
| UniProt Protein Function: | MRPL20: a mitochondrial ribosomal protein encoded by a nuclear gene that helps in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 21q. [provided by RefSeq, Jul 2008]Protein type: MitochondrialChromosomal Location of Human Ortholog: 1p36.3-p36.2Cellular Component: mitochondrial inner membrane; mitochondrial ribosome; mitochondrionMolecular Function: protein binding; rRNA binding; structural constituent of ribosomeBiological Process: mitochondrial translation; organelle organization and biogenesis; ribosomal large subunit assembly and maintenance |
| UniProt Protein Details: | |
| NCBI Summary: | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 21q. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016] |
| UniProt Code: | Q9BYC9 |
| NCBI GenInfo Identifier: | 26638657 |
| NCBI Gene ID: | 55052 |
| NCBI Accession: | NP_060441.2 |
| UniProt Secondary Accession: | Q9BYC9,B2RE41, B7Z746 |
| UniProt Related Accession: | Q9BYC9 |
| Molecular Weight: | 18,099 Da |
| NCBI Full Name: | 39S ribosomal protein L20, mitochondrial isoform 1 |
| NCBI Synonym Full Names: | mitochondrial ribosomal protein L20 |
| NCBI Official Symbol: | MRPL20 |
| NCBI Official Synonym Symbols: | L20mt; MRP-L20 |
| NCBI Protein Information: | 39S ribosomal protein L20, mitochondrial |
| UniProt Protein Name: | 39S ribosomal protein L20, mitochondrial |
| UniProt Synonym Protein Names: | |
| Protein Family: | 39S ribosomal protein |
| UniProt Gene Name: | MRPL20 |
| UniProt Entry Name: | RM20_HUMAN |
| Antibodies |
| MRPL20 Antibody (PACO01095) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
