MRPL14 Antibody (PACO28338)
- SKU:
- PACO28338
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | MRPL14 Antibody (PACO28338) |
| Antibody SKU: | PACO28338 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Recombinant Human 39S ribosomal protein L14, mitochondrial protein (1-145AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: MRPL14 antibody at 2µg/ml Lane 1: Hela whole cell lysate Lane 2: HepG2 whole cell lysate Lane 3: Mouse liver tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 16 kDa Observed band size: 16 kDa . |
 | Immunohistochemistry of paraffin-embedded human colon cancer using PACO28338 at dilution of 1:100. |
| Background: | Forms part of 2 intersubunit bridges in the assembled ribosome. Upon binding to MALSU1 intersubunit bridge formation is blocked, preventing ribosome formation and repressing translation (Probable). |
| Synonyms: | 39S ribosomal protein L14, mitochondrial (L14mt) (MRP-L14) (39S ribosomal protein L32, mitochondrial) (L32mt) (MRP-L32) (Mitochondrial large ribosomal subunit protein uL14m), MRPL14, MRPL32 RPML32 |
| UniProt Protein Function: | MRPL14: Forms part of 2 intersubunit bridges in the assembled ribosome. Upon binding to MALSU1 intersubunit bridge formation is blocked, preventing ribosome formation and repressing translation (Probable). Belongs to the ribosomal protein L14P family.Protein type: TranslationChromosomal Location of Human Ortholog: 6p21.3Cellular Component: mitochondrial inner membrane; ribosomeMolecular Function: structural constituent of ribosomeBiological Process: mitochondrial translation; organelle organization and biogenesis |
| UniProt Protein Details: | |
| NCBI Summary: | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found at 17p13.3. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q6P1L8 |
| NCBI GenInfo Identifier: | 55769543 |
| NCBI Gene ID: | 64928 |
| NCBI Accession: | NP_115487.2 |
| UniProt Secondary Accession: | Q6P1L8,Q96Q72, B2R575 |
| UniProt Related Accession: | Q6P1L8 |
| Molecular Weight: | 15,948 Da |
| NCBI Full Name: | 39S ribosomal protein L14, mitochondrial |
| NCBI Synonym Full Names: | mitochondrial ribosomal protein L14 |
| NCBI Official Symbol: | MRPL14 |
| NCBI Official Synonym Symbols: | L14mt; L32mt; MRPL32; RMPL32; RPML32; MRP-L14; MRP-L32 |
| NCBI Protein Information: | 39S ribosomal protein L14, mitochondrial; 39S ribosomal protein L32, mitochondrial |
| UniProt Protein Name: | 39S ribosomal protein L14, mitochondrial |
| UniProt Synonym Protein Names: | 39S ribosomal protein L32, mitochondrial |
| Protein Family: | 39S ribosomal protein |
| UniProt Gene Name: | MRPL14 |
| UniProt Entry Name: | RM14_HUMAN |
| Antibodies |
| MRPL14 Antibody (PACO01091) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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