Name: MRPL14 Antibody (PACO28338)
SKU: PACO28338
Availability: OutOfStock

Antibody Name:	MRPL14 Antibody (PACO28338)
Antibody SKU:	PACO28338
Size:	50ug
Host Species:	Rabbit
Tested Applications:	ELISA, WB, IHC
Recommended Dilutions:	ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200
Species Reactivity:	Human, Mouse
Immunogen:	Recombinant Human 39S ribosomal protein L14, mitochondrial protein (1-145AA)

Form:	Liquid
Storage Buffer:	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:	>95%, Protein G purified
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

	Western blot All lanes: MRPL14 antibody at 2µg/ml Lane 1: Hela whole cell lysate Lane 2: HepG2 whole cell lysate Lane 3: Mouse liver tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 16 kDa Observed band size: 16 kDa .
	Immunohistochemistry of paraffin-embedded human colon cancer using PACO28338 at dilution of 1:100.

Background:	Forms part of 2 intersubunit bridges in the assembled ribosome. Upon binding to MALSU1 intersubunit bridge formation is blocked, preventing ribosome formation and repressing translation (Probable).
Synonyms:	39S ribosomal protein L14, mitochondrial (L14mt) (MRP-L14) (39S ribosomal protein L32, mitochondrial) (L32mt) (MRP-L32) (Mitochondrial large ribosomal subunit protein uL14m), MRPL14, MRPL32 RPML32

UniProt Protein Function:	MRPL14: Forms part of 2 intersubunit bridges in the assembled ribosome. Upon binding to MALSU1 intersubunit bridge formation is blocked, preventing ribosome formation and repressing translation (Probable). Belongs to the ribosomal protein L14P family.Protein type: TranslationChromosomal Location of Human Ortholog: 6p21.3Cellular Component: mitochondrial inner membrane; ribosomeMolecular Function: structural constituent of ribosomeBiological Process: mitochondrial translation; organelle organization and biogenesis
UniProt Protein Details:
NCBI Summary:	Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found at 17p13.3. [provided by RefSeq, Jul 2008]
UniProt Code:	Q6P1L8
NCBI GenInfo Identifier:	55769543
NCBI Gene ID:	64928
NCBI Accession:	NP_115487.2
UniProt Secondary Accession:	Q6P1L8,Q96Q72, B2R575
UniProt Related Accession:	Q6P1L8
Molecular Weight:	15,948 Da
NCBI Full Name:	39S ribosomal protein L14, mitochondrial
NCBI Synonym Full Names:	mitochondrial ribosomal protein L14
NCBI Official Symbol:	MRPL14
NCBI Official Synonym Symbols:	L14mt; L32mt; MRPL32; RMPL32; RPML32; MRP-L14; MRP-L32
NCBI Protein Information:	39S ribosomal protein L14, mitochondrial; 39S ribosomal protein L32, mitochondrial
UniProt Protein Name:	39S ribosomal protein L14, mitochondrial
UniProt Synonym Protein Names:	39S ribosomal protein L32, mitochondrial
Protein Family:	39S ribosomal protein
UniProt Gene Name:	MRPL14
UniProt Entry Name:	RM14_HUMAN