MRPL14 Antibody (PACO22086)
- SKU:
- PACO22086
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | MRPL14 Antibody (PACO22086) |
| Antibody SKU: | PACO22086 |
| Size: | 100ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Synthesized peptide derived from internal of human MRPL14. |
| Form: | Liquid |
| Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot analysis of extracts from HeLa cells, COLO cells and 293 cells, using MRPL14 antibody. |
| Background: | Forms part of 2 intersubunit bridges in the assembled ribosome. Upon binding to MALSU1 intersubunit bridge formation is blocked, preventing ribosome formation and repressing translation Probable. |
| Synonyms: | 39S ribosomal protein L14; mitochondrial; L14mt; MRP-L14; MRP-L32 |
| UniProt Protein Function: | MRPL14: Forms part of 2 intersubunit bridges in the assembled ribosome. Upon binding to MALSU1 intersubunit bridge formation is blocked, preventing ribosome formation and repressing translation (Probable). Belongs to the ribosomal protein L14P family.Protein type: TranslationChromosomal Location of Human Ortholog: 6p21.3Cellular Component: mitochondrial inner membrane; ribosomeMolecular Function: structural constituent of ribosomeBiological Process: mitochondrial translation; organelle organization and biogenesis |
| UniProt Protein Details: | |
| NCBI Summary: | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found at 17p13.3. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q6P1L8 |
| NCBI GenInfo Identifier: | 55769543 |
| NCBI Gene ID: | 64928 |
| NCBI Accession: | NP_115487.2 |
| UniProt Secondary Accession: | Q6P1L8,Q96Q72, B2R575 |
| UniProt Related Accession: | Q6P1L8 |
| Molecular Weight: | 15,948 Da |
| NCBI Full Name: | 39S ribosomal protein L14, mitochondrial |
| NCBI Synonym Full Names: | mitochondrial ribosomal protein L14 |
| NCBI Official Symbol: | MRPL14 |
| NCBI Official Synonym Symbols: | L14mt; L32mt; MRPL32; RMPL32; RPML32; MRP-L14; MRP-L32 |
| NCBI Protein Information: | 39S ribosomal protein L14, mitochondrial; 39S ribosomal protein L32, mitochondrial |
| UniProt Protein Name: | 39S ribosomal protein L14, mitochondrial |
| UniProt Synonym Protein Names: | 39S ribosomal protein L32, mitochondrial |
| Protein Family: | 39S ribosomal protein |
| UniProt Gene Name: | MRPL14 |
| UniProt Entry Name: | RM14_HUMAN |
| Antibodies |
| MRPL14 Antibody (PACO01091) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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