Description
Antibody Name: | MRNIP Antibody (PACO36826) |
Antibody SKU: | PACO36826 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
Species Reactivity: | Human, Mouse |
Immunogen: | Recombinant Human MRN complex-interacting protein (1-200AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: MRNIP antibody at 4µg/ml. Lane 1: Mouse kidney tissue. Lane 2: Mouse heart tissue. Lane 3: Hela whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 38, 30, 32 kDa. Observed band size: 38 kDa. |
Background: | Plays a role in the cellular response to DNA damage and the maintenance of genome stability through its association with the MRN damage-sensing complex. Promotes chromatin loading and activity of the MRN complex to facilitate subsequent ATM-mediated DNA damage response signaling and DNA repair. |
Synonyms: | MRN complex-interacting protein (MRN-interacting protein), MRNIP, C5orf45 |
UniProt Protein Function: | |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q6NTE8 |
NCBI GenInfo Identifier: | 63082033 |
NCBI Gene ID: | 51149 |
NCBI Accession: | NP_057259 |
UniProt Secondary Accession: | Q6NTE8 |
UniProt Related Accession: | Q6NTE8 |
Molecular Weight: | 38kDa |
NCBI Full Name: | MRN complex-interacting protein isoform 1 |
NCBI Synonym Full Names: | MRN complex interacting protein |
NCBI Official Symbol: | MRNIP |
NCBI Official Synonym Symbols: | C5orf45 |
NCBI Protein Information: | MRN complex-interacting protein |
UniProt Protein Name: | UPF0544 protein C5orf45 |
UniProt Synonym Protein Names: | |
Protein Family: | |
UniProt Gene Name: | C5orf45 |
UniProt Entry Name: | CE045_HUMAN |