mrcA Antibody (PACO49154)
- SKU:
- PACO49154
- Product Type:
- Antibody
- Reactivity:
- Bacteria - Escherichia coli
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | mrcA Antibody (PACO49154) |
| Antibody SKU: | PACO49154 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Escherichia coli |
| Immunogen: | Recombinant Escherichia coli Penicillin-binding protein 1A protein (229-529AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits). |
| Synonyms: | Penicillin-binding protein 1A (PBP-1a) (PBP1a) [Includes: Penicillin-insensitive transglycosylase (EC 2.4.1.129) (Peptidoglycan TGase); Penicillin-sensitive transpeptidase (EC 3.4.16.4) (DD-transpeptidase)], mrcA, ponA |
| UniProt Protein Function: | Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits). |
| UniProt Protein Details: | |
| NCBI Summary: | The N-terminal transglycosylase activity polymerizes the glycan backbone and is penicillin-insensitive. [More information is available at EcoGene: EG10748]. PBP1A, the product of the mrcA gene, is a bifunctional, inner membrane enzyme catalyzing the transglycosylation and transpeptidation of murein (peptidoglycan) precursors in the formation of the murein sacculus. [More information is available at EcoCyc: EG10748]. |
| UniProt Code: | P02918 |
| NCBI GenInfo Identifier: | 162135911 |
| NCBI Gene ID: | 947907 |
| NCBI Accession: | NP_417855.4 |
| UniProt Secondary Accession: | P02918,P76688, Q2M761 |
| UniProt Related Accession: | P02918 |
| Molecular Weight: | 49.43 kDa |
| NCBI Full Name: | penicillin-binding protein 1a, murein transglycosylase and transpeptidase |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | mrcA |
| NCBI Official Synonym Symbols: | ECK3383; JW3359; ponA |
| NCBI Protein Information: | penicillin-binding protein 1a, murein transglycosylase and transpeptidase |
| UniProt Protein Name: | Penicillin-binding protein 1A |
| UniProt Synonym Protein Names: | DD-transpeptidase |
| Protein Family: | Penicillin-binding protein |
| UniProt Gene Name: | mrcA |
| UniProt Entry Name: |
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