Antibody Name:	MPP6 Antibody (PACO20846)
Antibody SKU:	PACO20846
Size:	50ul
Host Species:	Rabbit
Tested Applications:	ELISA, WB, IHC
Recommended Dilutions:	ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100
Species Reactivity:	Human, Mouse
Immunogen:	Synthetic peptide of human MPP6

Form:	Liquid
Storage Buffer:	-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:	Antigen affinity purification
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

	Gel: 8%SDS-PAGE,Lysate: 40 μgPrimary antibody: PACO20846(MPP6 Antibody) at dilution 1/250 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 1 minute.
	The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO20846(MPP6 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200).

Background:

Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling proteins. All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies, DLG-like (see DLG1; MIM 601014), ZO1-like (see TJP1; MIM 601009), p55-like (see MPP1; MIM 305360), and LIN2-like (see CASK; MIM 300172), based on their size and the presence of additional domains. MPP6 is a member of the p55-like MAGUK subfamily (Tseng et al., 2001 [PubMed 11311936]).

Synonyms:

membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)

UniProt Protein Function:	VAM-1: a membrane-associated of the MAGUK family. Interacts with Lin7, which localizes to postsynaptic densities of neurons and epithelial cell-cell junctions.
UniProt Protein Details:	Protein type:Motility/polarity/chemotaxis; Adaptor/scaffold Chromosomal Location of Human Ortholog: 7p15 Molecular Function:protein binding
NCBI Summary:	Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling proteins. All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies, DLG-like (see DLG1; MIM 601014), ZO1-like (see TJP1; MIM 601009), p55-like (see MPP1; MIM 305360), and LIN2-like (see CASK; MIM 300172), based on their size and the presence of additional domains. MPP6 is a member of the p55-like MAGUK subfamily (Tseng et al., 2001 [PubMed 11311936]).[supplied by OMIM, Mar 2008]
UniProt Code:	Q9NZW5
NCBI GenInfo Identifier:	42560556
NCBI Gene ID:	51678
NCBI Accession:	Q9NZW5.2
UniProt Secondary Accession:	Q9NZW5,Q9H0E1, A4D157,
UniProt Related Accession:	Q9NZW5
Molecular Weight:	61,117 Da
NCBI Full Name:	MAGUK p55 subfamily member 6
NCBI Synonym Full Names:	membrane palmitoylated protein 6
NCBI Official Symbol:	MPP6
NCBI Official Synonym Symbols:	VAM1; p55T; PALS2; VAM-1
NCBI Protein Information:	MAGUK p55 subfamily member 6
UniProt Protein Name:	MAGUK p55 subfamily member 6
UniProt Synonym Protein Names:	Veli-associated MAGUK 1; VAM-1
Protein Family:	MAGUK p55 subfamily
UniProt Gene Name:	MPP6
UniProt Entry Name:	MPP6_HUMAN

Antibodies	ELISA Kits
Anti-MPP6 Antibody (CAB10509)	Human VAM1 / MPP6 / MAGUK p55 subfamily member 6 ELISA Kit
MPP6 Antibody (PACO10557)	Human MAGUK p55 subfamily member 6 (MPP6) ELISA Kit

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)