Growth Factors & Cytokines Recombinant Proteins
Mouse TNF-alpha/TNFA Recombinant Protein ((RPES3592)
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- SKU:
- RPES3592
- Product Type:
- Recombinant Protein
- Species:
- Mouse
- Research Area:
- Growth Factors & Cytokines
Description
system_update_altDatasheet
Mouse TNF-alpha/TNFA Recombinant Protein (
Tumor Necrosis Factor (TNF) is a member of the Tumor Necrosis Factor family. TNF exists as a homotrimer and interacts with SPPL2B. TNF is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. TNF is a key cytokine in the development of several inflammatory disorders. It contributes to the development of type 2 diabetes throught its effects on insulin resistance and fatty acid metabolism.
| Product Name: | Mouse TNF-alpha/TNFA Recombinant Protein ((RPES3592) |
| Product Code: | RPES3592 |
| Size: | 10µg |
| Species: | Mouse |
| Expressed Host: | E.coli |
| Synonyms: | Tumor Necrosis Factor, Cachectin, TNF-Alpha, Tumor Necrosis Factor Ligand Superfamily Member 2, TNF-a, Tumor Necrosis Factor, Membrane Form, Tumor Necrosis Factor, Tnf,Tnfsf2,DIF,TNF-alpha,Tnfa,TNFalpha,Tnfsf1a,TNFSF2 |
| Accession: | P06804 |
| Sequence: | Asp89-Leu235 |
| Activity: | Measured in a cytotoxicity assay using L?929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D. The ED50 for this effect is 2-8 pg/ml. |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Mouse Tumor Necrosis Factor alpha is produced by our E.coli expression system and the target gene encoding Asp89-Leu235 is expressed. |
| Purity: | > 95 % as determined by SDS-PAGE |
| Mol Mass: | 16.4 kDa |
| AP Mol Mass: | 14 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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