Mouse ST6GALNAC2 Recombinant Protein (RPES2219)
- SKU:
- RPES2219
- Product Type:
- Recombinant Protein
- Species:
- Mouse
Description
system_update_altDatasheet
Mouse ST6GALNAC2 Recombinant Protein
Alpha-N-acetylgalactosaminide alpha -2,6-sialyltransferase 2, is a type?II membrane protein localized in the Golgi network and catalyzes 2,6-sialylation of the Tn antigen. Sialyl-Tn antigen is highly expressed in several human carcinomas and is associated with carcinoma aggressiveness and poor prognosis.?it has been reported that disregulation of this gene is involved in the pathogenesis of IgA nephropathy, a common kidney disease that occurs when antibody IgA accumulates in kidneys (4). The enzyme may also be used to synthesize a cancer vaccine.
| Product Name: | Mouse ST6GALNAC2 Recombinant Protein (RPES2219) |
| Product Code: | RPES2219 |
| Size: | 10µg |
| Species: | Mouse |
| Expressed Host: | Human Cells |
| Synonyms: | Gal-beta-1,3-GalNAc alpha-2,6-sialyltransferase,GalNAc alpha-2,6-sialyltransferase II,ST6GalNAc II,Sialyltransferase 7B,SIAT7-B,II,Siat7,Siat7b,ST6GalNAc |
| Accession: | P70277 |
| Sequence: | Ser28-Arg373 |
| Fusion tag: | C-His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Mouse ST6GALNAC2 is produced by our Mammalian expression system and the target gene encoding Ser28-Arg373 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 95% as determined by reducing SDS-PAGE. |
| Mol Mass: | 40.4 kDa |
| AP Mol Mass: | 45 kDa |
| Formulation: | Supplied as a 0.2 µm filtered solution of 50mMTris,150mMNaCl,pH7.5. |
| Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C. |
| Stability and Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
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