Description
Product Name: | Mouse SERPINA9 Recombinant Protein |
Product Code: | RPPB4633 |
Size: | 5µg |
Species: | Mouse |
Target: | SERPINA9 |
Synonyms: | Serpin A9, Serpina9, SERPINA9. |
Source: | Sf9 Insect cells |
Physical Appearance: | Sterile Filtered colorless solution. |
Formulation: | SERPINA9 protein solution (0.25mg/ml) contains PhosphateBuffered Saline (pH 7.4) and 10% glycerol. |
Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.�For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).�Avoid multiple freeze-thaw cycles. |
Purity: | Greaterthan 85.0% as determined by SDS-PAGE. |
Amino Acid Sequence: | NPYNQESSHL PSMKKNPASQ VSPSNTRFSF LLYQRLAQEN PGQNILFSPVSISTSLAMLS LGARSATKTQ ILRTLGFNFT WVSEPTIHMG FEYLVRSLNK CHQGRELRMG SVLFIRKELQLQATFLDRVK KLYGAKVFSE DFSNAATAQA QINSYVEKET KGKVVDVIQD LDSQTAMVLV NHIFFKANWT QPFSTANTNK SFPFLLSKGT TVHVPMMHQT ESFAFGVDKELGCSILQMDY RGDAVAFFVL PGKGKMRQLE KSLSARRLRK WSRSLQKRWI KVFIPKFSIS ASYNLETILPKMGIRDAFNS NADFSGITKT HFLQVSKAAH KAVLDVSEEG TEAAAATTTK LIVRSRDTPS SIIAFKEPFL ILLLDKNTESVLFLGKVENP RKMLEHHHHH H |
UniProt Code: | Q9D7D2 |
Serpin Peptidase Inhibitor, Clade AMember 9, also known as serpin A9, belongs to the Serpin superfamily of serineprotease inhibitors. Serpins are the most extensively distributed superfamilyof protease inhibitors which use a conformational modification to inhibittarget enzymes. Serpins are known to inhibit serine proteases as well asinhibiting caspases in addition to papain-like cysteine proteases. Serpins areconformational labile and numerous of the disease-linked mutations of serpinsoutcome in misfolding or in pathogenic, inactive polymers. serpin A9demonstrates inhibition towards trypsin, thrombin, as well as plasmin and bindsDNA and heparin.
SERPINA9 Mouse Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 401 amino acids (26-418 a.a) and having a molecular mass of 45.2kDa (Molecular size on SDS-PAGE will appear at approximately 50-70kDa).SERPINA9 is fused to an 8 amino acid His-tag at C-terminus & purified by proprietary chromatographic techniques.