Enzymes Recombinant Proteins

Mouse SEPSECS Recombinant Protein (RPPB2269)

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SKU:
RPPB2269
Product Type:
Recombinant Protein
Species:
Mouse
Uniprot:
Q6P6M7
Research Area:
Enzymes

Description

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Product Name:Mouse SEPSECS Recombinant Protein
Product Code:RPPB2269
Size:5µg
Species:Mouse
Target:SEPSECS
Synonyms:AA986712, D5Ertd135e, SecS, SLA, SLA/LP autoantigen, SLA-p35, Selenocysteinyl-tRNA(Sec) synthase, Selenocysteine synthase, Liver-pancreas antigen, Soluble liver antigen, Sec synthase, UGA suppressor tRNA-associated protein, SepSecS.�
Source:Escherichia Coli
Physical Appearance:Sterile Filtered clear solution.
Formulation:The SEPSECS protein solution (0.25 mg/ml) is formulated in 20mM Tris-HCl buffer (pH7.5) 1mM DTT, 0.2M NaCl and 50% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.�For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles
Purity:Greater than 90% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSMNPESFA AGERRVSPAY VRQGCEARRA HEHLIRLLLE QGKCPEDGWD ESTLELFLHE LAVMDSNNFL GNCGVGEREG RVASALVARR HYRFIHGIGR SGDISAVQPK AAGSSLLNKI TNSLVLNVIK LAGVHSVASC FVVPMATGMS LTLCFLTLRHKRPKAKYIIW PRIDQKSCFK SMVTAGFEPV VIENVLEGDE LRTDLKAVEA KIQELGPEHI LCLHSTTACF APRVPDRLEE LAVICANYDI PHVVNNAYGL QSSKCMHLIQ QGARVGRIDA FVQSLDKNFM VPVGGAIIAG FNEPFIQDIS KMYPGRASAS PSLDVLITLL SLGCSGYRKLLKERKEMFVY LSTQLKKLAE AHNERLLQTP HNPISLAMTL KTIDGHHDKA VTQLGSMLFT RQVSGARAVP LGNVQTVSGH TFRGFMSHAD NYPCAYLNAA AAIGMKMQDV DLFIKRLDKC LNIVRKEQTR ASVVSGADRN KAEDADIEEM ALKLDDVLGD VGQGPAL

SEPSECS catalyzes the last step of sec synthesis by converting O-phosphoseryl-tRNA(sec) to selenocysteinyl-tRNA(sec) using selenophosphate as the selenium donor. Furthermore, SEPSECS protein is considered a specific marker of autoimmune hepatitis.

SEPSECS produced in E.Coli is a single, non-glycosylated polypeptide chain containing 527 amino acids (1-504 a.a.) and having a molecular mass of 57.7kDa.SEPSECS is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
UniProt Protein Details:
NCBI Summary:
UniProt Code:Q6P6M7
NCBI GenInfo Identifier:62287885
NCBI Gene ID:211006
NCBI Accession:Q6P6M7.2
UniProt Secondary Accession:Q6P6M7
UniProt Related Accession:Q6P6M7
Molecular Weight:57.7 kDa (527aa), confirmed by MALDI-TOF
NCBI Full Name:O-phosphoseryl-tRNA(Sec) selenium transferase
NCBI Synonym Full Names:Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase
NCBI Official Symbol:Sepsecs��
NCBI Official Synonym Symbols:SLA; SecS; AA986712; D5Ertd135e��
NCBI Protein Information:O-phosphoseryl-tRNA(Sec) selenium transferase
UniProt Protein Name:O-phosphoseryl-tRNA(Sec) selenium transferase
UniProt Synonym Protein Names:Selenocysteine synthase; Sec synthase; Selenocysteinyl-tRNA(Sec) synthase; Sep-tRNA:Sec-tRNA synthase; SepSecS; UGA suppressor tRNA-associated protein
Protein Family:O-phosphoseryl-tRNA(Sec) selenium transferase
UniProt Gene Name:Sepsecs��
UniProt Entry Name:
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