Enzymes Recombinant Proteins
Mouse SEPSECS Recombinant Protein (RPPB2269)
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- SKU:
- RPPB2269
- Product Type:
- Recombinant Protein
- Species:
- Mouse
- Uniprot:
- Q6P6M7
- Research Area:
- Enzymes
Description
| Product Name: | Mouse SEPSECS Recombinant Protein |
| Product Code: | RPPB2269 |
| Size: | 5µg |
| Species: | Mouse |
| Target: | SEPSECS |
| Synonyms: | AA986712, D5Ertd135e, SecS, SLA, SLA/LP autoantigen, SLA-p35, Selenocysteinyl-tRNA(Sec) synthase, Selenocysteine synthase, Liver-pancreas antigen, Soluble liver antigen, Sec synthase, UGA suppressor tRNA-associated protein, SepSecS.� |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | The SEPSECS protein solution (0.25 mg/ml) is formulated in 20mM Tris-HCl buffer (pH7.5) 1mM DTT, 0.2M NaCl and 50% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.�For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles |
| Purity: | Greater than 90% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMNPESFA AGERRVSPAY VRQGCEARRA HEHLIRLLLE QGKCPEDGWD ESTLELFLHE LAVMDSNNFL GNCGVGEREG RVASALVARR HYRFIHGIGR SGDISAVQPK AAGSSLLNKI TNSLVLNVIK LAGVHSVASC FVVPMATGMS LTLCFLTLRHKRPKAKYIIW PRIDQKSCFK SMVTAGFEPV VIENVLEGDE LRTDLKAVEA KIQELGPEHI LCLHSTTACF APRVPDRLEE LAVICANYDI PHVVNNAYGL QSSKCMHLIQ QGARVGRIDA FVQSLDKNFM VPVGGAIIAG FNEPFIQDIS KMYPGRASAS PSLDVLITLL SLGCSGYRKLLKERKEMFVY LSTQLKKLAE AHNERLLQTP HNPISLAMTL KTIDGHHDKA VTQLGSMLFT RQVSGARAVP LGNVQTVSGH TFRGFMSHAD NYPCAYLNAA AAIGMKMQDV DLFIKRLDKC LNIVRKEQTR ASVVSGADRN KAEDADIEEM ALKLDDVLGD VGQGPAL |
SEPSECS catalyzes the last step of sec synthesis by converting O-phosphoseryl-tRNA(sec) to selenocysteinyl-tRNA(sec) using selenophosphate as the selenium donor. Furthermore, SEPSECS protein is considered a specific marker of autoimmune hepatitis.
SEPSECS produced in E.Coli is a single, non-glycosylated polypeptide chain containing 527 amino acids (1-504 a.a.) and having a molecular mass of 57.7kDa.SEPSECS is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q6P6M7 |
| NCBI GenInfo Identifier: | 62287885 |
| NCBI Gene ID: | 211006 |
| NCBI Accession: | Q6P6M7.2 |
| UniProt Secondary Accession: | Q6P6M7 |
| UniProt Related Accession: | Q6P6M7 |
| Molecular Weight: | 57.7 kDa (527aa), confirmed by MALDI-TOF |
| NCBI Full Name: | O-phosphoseryl-tRNA(Sec) selenium transferase |
| NCBI Synonym Full Names: | Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase |
| NCBI Official Symbol: | Sepsecs�� |
| NCBI Official Synonym Symbols: | SLA; SecS; AA986712; D5Ertd135e�� |
| NCBI Protein Information: | O-phosphoseryl-tRNA(Sec) selenium transferase |
| UniProt Protein Name: | O-phosphoseryl-tRNA(Sec) selenium transferase |
| UniProt Synonym Protein Names: | Selenocysteine synthase; Sec synthase; Selenocysteinyl-tRNA(Sec) synthase; Sep-tRNA:Sec-tRNA synthase; SepSecS; UGA suppressor tRNA-associated protein |
| Protein Family: | O-phosphoseryl-tRNA(Sec) selenium transferase |
| UniProt Gene Name: | Sepsecs�� |
| UniProt Entry Name: |
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