Mouse Semaphorin-4A/SEMA4A Recombinant Protein (RPES2852)

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SKU:
RPES2852
Product Type:
Recombinant Protein
Species:
Mouse

Description

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Mouse Semaphorin-4A/SEMA4A Recombinant Protein

Semaphorin-4A (SEMA4A) belongs to the semaphorin family which contains a Ig-like C2-type domain, a PSI domain and a Sema domain. SEMA4A is expressed from day 10 in the embryo, and low levels are found between days 10-12. SEMA4A is a cell surface receptor for PLXNB1, PLXNB2, PLXNB3 and PLXND1 that plays an important role in cell-cell signaling. It plays a role in priming antigen-specific T-cells, promotes differentiation of Th1 T-helper cells, and thereby contributes to adaptive immunity. SEMA4A promotes phosphorylation of TIMD2, inhibits angiogenesis, and promotes axon growth cone collapse, Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons.

Product Name:Mouse Semaphorin-4A/SEMA4A Recombinant Protein (RPES2852)
Product Code:RPES2852
Size:10µg
Species:Mouse
Expressed Host:Human Cells
Synonyms:Semaphorin-4A,Semaphorin-B,Sema B,Sema4a,Semab, SemB
Accession:Q62178
Sequence: Thr33-His682
Fusion tag:C-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Mouse Semaphorin 4A is produced by our Mammalian expression system and the target gene encoding Thr33-His682 is expressed with a 6His tag at the C-terminus.
Purity:> 95 % as determined by SDS-PAGE
Mol Mass:72.7 kDa
AP Mol Mass:70-90 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of 20mM PB,150mM NaCl,pH7.4.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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